PMID: 16636645Apr 26, 2006Paper

Economic evaluation of drug-eluting stents in Japan

The Keio Journal of Medicine
Shunya Ikeda, Mia Kobayashi

Abstract

Stenting with a sirolimus-eluting stent (SES) dramatically reduces the risk of restenosis compared to bare metal stent (BMS) implantation. However, before SES can be widely adopted in clinical practice, it is essential to conduct an economic evaluation of this effective but expensive device. Our study was undertaken to estimate the three-year cumulative medical costs of stenting using SES compared to BMS. The data on clinical sequelae of stenting using BMS were derived from our previous study, based on data collected from three Japanese hospitals. We estimated that the probability of PTCA required for revascularization would be 0.224 times in SES implantation compared than in BMS implantation based on the SIRIUS study result. The medical costs for procedures were obtained from published articles and were adjusted to the March 2005 level. Our simulation showed the expected three-year cumulative medical cost per patient to be approximately 200,000 yen lower in the SES group(2,233,000 yen ) than in the BMS group (2,431,000 yen ). Sensitivity analyses with different presumptions confirmed that the economic advantage of SES over BMS was quite robust. We concluded that the use of SES would be a cost-saving option as compared with BMS...Continue Reading

References

May 10, 2001·Journal of the American College of Cardiology·F KiemeneijM A Morel
May 10, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·Miwako ShiharaUNKNOWN Japanese Coronary Intervention Study (JCIS) Group
May 10, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·Hideaki ShigematsuUNKNOWN Japanese Coronary Intervention Study (JCIS) Group
Jun 7, 2002·The New England Journal of Medicine·Marie-Claude MoriceUNKNOWN RAVEL Study Group. Randomized Study with the Sirolimus-Coated Bx Velocity Balloon-Expandable Stent in the Treatment of Patie
Jan 16, 2003·Heart·J GunnD C Cumberland
Apr 12, 2003·The Lancet Oncology·Peter LittlejohnsUNKNOWN UK National Institute for Clinical Excellence
Jun 25, 2003·Circulation·Pedro A LemosJ Eduardo Sousa
Jun 25, 2003·Circulation·William W O'Neill, Martin B Leon
Jun 25, 2003·Circulation·Dean J Kereiakes
Oct 3, 2003·The New England Journal of Medicine·Jeffrey W MosesUNKNOWN SIRIUS Investigators
Mar 5, 2004·American Heart Journal·David F KongRobert M Califf

❮ Previous
Next ❯

Citations

Dec 21, 2006·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Suzanne LigthartJames M Brophy
Dec 3, 2009·International Heart Journal·Kazumasa SugimotoIssei Komuro
May 28, 2016·Cardiovascular Intervention and Therapeutics·Tomoyuki TakuraShinsuke Nanto
Oct 18, 2006·Circulation·Mark J Eisenberg
May 28, 2011·American Journal of Botany·Anna BucharováPremysl Tájek

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.