Economic evaluation of neutral-pH, low-glucose degradation product peritoneal dialysis solutions compared with standard solutions: a secondary analysis of the balANZ Trial

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Kirsten HowardDavid W Johnson

Abstract

Biocompatible solutions may lower peritonitis rates, but are more costly than conventional solutions. The aim of the present study was to assess the additional costs and health outcomes of biocompatible over conventional solutions in incident peritoneal dialysis patients to guide practice decisions. Secondary economic evaluation of a randomized controlled trial. 185 participants in the balANZ trial. Cost-effectiveness of biocompatible compared to standard solution over the 2 years using an Australian health care funder perspective. Intervention group received biocompatible solutions and control group received standard solutions over 2 years. Costs included dialysis charges, costs of treating peritonitis, non-peritonitis-related hospital stays, and medication. Peritonitis was the health outcome of interest; incremental cost-effectiveness ratios were reported in terms of the additional cost per additional patient avoiding peritonitis at 2 years. Mean total per-patient costs were A$57,451 and A$53,930 for the biocompatible and standard-solution groups, respectively. The base-case analysis indicated an incremental cost of A$17,804 per additional patient avoiding peritonitis at 2 years for biocompatible compared to standard solution...Continue Reading

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Citations

Jul 15, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Anna FrancisDavid W Johnson
Nov 2, 2016·Journal of the American Society of Nephrology : JASN·Rajnish MehrotraDavid W Johnson
Oct 11, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Claus Peter Schmitt, Christoph Aufricht
Feb 6, 2017·Seminars in Nephrology·Cheuk Chun Szeto, David W Johnson
Jul 6, 2017·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Charlotte E GranthamJames O Burton
Sep 24, 2016·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Melissa NataatmadjaDavid W Johnson
May 16, 2017·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Yeoungjee ChoDavid W Johnson
Oct 27, 2018·The Cochrane Database of Systematic Reviews·Htay HtayYeoungjee Cho
Oct 6, 2018·Scientific Reports·Surapon NochaiwongUNKNOWN Thai Renal Outcomes Research (THOR) Investigators

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