Economic health care costs of blood culture contamination: A systematic review

American Journal of Infection Control
Casey DempseyKevin W Garey

Abstract

Blood culture contamination with gram-positive organisms is a common occurrence in patients suspected of bloodstream infections, especially in emergency departments. Although numerous research studies have investigated the cost implications of blood culture contamination, a contemporary systematic review of the literature has not been performed. The aim of this project was to perform a systematic review of the published literature on the economic costs of blood culture contamination. PubMed was searched (January 1, 1978, to July 15, 2018) using the search terms "blood culture contamination" or "false-positive blood cultures." Articles were title searched and abstracts were reviewed for eligible articles that reported immediate or downstream economic costs of blood culture contamination. The PubMed search identified 151 relevant articles by title search, with 49 articles included after abstract review. From the studies included, overall blood culture contamination rates ranged from 0.9%-41%. Up to 59% of patients received unnecessary treatment with parenteral vancomycin as a result of blood culture contamination, resulting in increased pharmacy charges between $210 and $12,611 per patient. Increases in total laboratory charges b...Continue Reading

Citations

Feb 14, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Ariel KenigSarah Israel
Dec 5, 2020·Animals : an Open Access Journal From MDPI·Alba GaspardoMarco Pietra
Jun 29, 2021·Transfusion·Isabella W MartinUNKNOWN SCARED Study Investigators on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative
Oct 28, 2021·Hospital Pediatrics·Prabi RajbhandariMatthew Garber

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