Economic impact of compliance to treatment with antidiabetes medication in type 2 diabetes mellitus: a review paper

Journal of Medical Economics
L BreitscheidelO Schöffski

Abstract

Suboptimal compliance and failure to persist with antidiabetes therapies are of potential economic significance. The present research aims to describe the impact of poor compliance and persistence with antidiabetes medications on the cost of healthcare or its components for patients with type 2 diabetes mellitus (T2DM). Literature search was conducted in PubMed for relevant articles published in the period between 1 January 2000 and 30 April 2009. Thus, it is possible that relevant articles not listed in PubMed, but available in other databases are not included in the current review. Studies describing economic consequence of compliance and/or persistence with pharmaceutical antidiabetes treatment were identified. The variability in the studies reviewed was high, making it extremely difficult to make a comparison between them. Of 449 articles corresponding to the primary search algorithm, 12 studies (all conducted in USA) fulfilled the inclusion criteria regarding the economic impact of compliance and/or persistence with treatment on the overall cost of T2DM care or its components. Compliance was assessed via medication possession ratio (MPR) in ten studies, where it ranged from 0.52 to 0.93 depending on regimen. Persistence wa...Continue Reading

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Citations

May 3, 2011·Journal of General Internal Medicine·Jerry L GrenardWalid F Gellad
Jun 28, 2014·Drug Design, Development and Therapy·Antoni Sicras-Mainar, Ruth Navarro-Artieda
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