Economic Implications of Widespread Expansion of Frozen Section Margin Analysis to Guide Surgical Resection in Women With Breast Cancer Undergoing Breast-Conserving Surgery

Journal of Oncology Practice
Judy C BougheyElizabeth B Habermann

Abstract

In the current health care environment, cost effectiveness is critically important in policy setting and care of patients. This study performed a health economic analysis to assess the implications to providers and payers of expanding the use of frozen section margin analysis to minimize reoperations for patients undergoing breast cancer lumpectomy. A health care economic impact model was built to assess annual costs associated with breast lumpectomy procedures with and without frozen section margin analysis to avoid reoperation. If frozen section margin analysis is used in 20% of breast lumpectomies and under a baseline assumption that 35% of initial lumpectomies without frozen section analysis result in reoperations, the potential annual cost savings are $18.2 million to payers and $0.4 million to providers. Under the same baseline assumption, if 100% of all health care facilities adopted the use of frozen section margin analysis for breast lumpectomy procedures, the potential annual cost savings are $90.9 million to payers and $1.8 million to providers. On the basis of 10,000 simulations, use of intraoperative frozen section margin analysis yields cost saving for payers and is cost neutral to slightly cost saving for provide...Continue Reading

References

May 17, 2005·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Alicia C SasserDavid Mallet
Oct 24, 2006·Annals of Surgical Oncology·Margaret ThompsonV Suzanne Klimberg
Apr 30, 2009·Health Affairs·Stephen ZuckermanKaren E Stockley
Jan 20, 2010·World Journal of Surgical Oncology·Mansher SinghAnneke T Schroen
Apr 28, 2010·Annals of Surgical Oncology·Julie A MargenthalerV Suzanne Klimberg
Aug 20, 2010·Journal of Pain & Palliative Care Pharmacotherapy·UNKNOWN Medicare Payment Advisory Commission U.S. Department Of Health And Human Services
Feb 3, 2012·JAMA : the Journal of the American Medical Association·Laurence E McCahillAdedayo A Onitilo

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Citations

Jun 15, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·E-S LeeD-Y Noh
Oct 20, 2018·Journal of Interprofessional Care·Katherine CarrollElizabeth Habermann
Sep 5, 2019·Annals of Surgical Oncology·Edibaldo Silva, Mona Tan
May 1, 2020·Annals of Surgical Oncology·Julia Schwarz, Hank Schmidt
Jun 28, 2018·Annals of Surgical Oncology·Anees B Chagpar, Lee G Wilke
Aug 2, 2021·Annals of Surgical Oncology·Swati A KulkarniXiao Han

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