PMID: 18185820Jan 11, 2008Paper

Economic outcomes associated with atypical antipsychotics in bipolar disorder: a systematic review

Primary Care Companion to the Journal of Clinical Psychiatry
Rachael L FleurenceKitty Rajagopalan

Abstract

Bipolar disorder is a serious condition that is costly to the health care system. Atypical antipsychotics are more expensive than conventional treatments. From a policy-making perspective, the additional cost must be justified by improved outcomes. The objective of this study was to conduct a systematic review to determine the relative costs and cost-effectiveness associated with atypical antipsychotics in bipolar disorder. We conducted a systematic review of the literature in PubMed and EMBASE from January 1985 through October 2005, including published studies and conference proceedings. Databases were searched using predefined terms. Studies were included if they were claims data analyses, trial-based economic evaluations, or cost-effectiveness analyses using models. Data were extracted using predefined tables. Fourteen studies were identified. Seven were medical claims database analyses, 4 were trial-based economic evaluations, and 3 were cost-effectiveness models. Eight of these studies were conference proceedings. The studies did not provide sufficient information to determine any ranking of interventions in terms of least to most costly in overall resource consumption or in terms of their relative cost-effectiveness. Wher...Continue Reading

Citations

May 21, 2010·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Kaveh MonshatPeter Bosanac
Sep 1, 2011·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·David CawthorpeMingshan Lu
May 20, 2015·Journal of Medical Economics·Krithika RajagopalanAntony Loebel
Sep 23, 2009·Journal of Medical Economics·Tatia Chay WoodwardArthur Lazarus

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