Economics of cancer biomarkers

Personalized Medicine
John E SchneiderDonald Chalfin

Abstract

Cancer accounts for approximately 13% of all deaths worldwide, and in 2010 the estimated total cost of cancer in the USA was more than US$263 billion. Biomarker use for screening, monitoring, diagnosis and treatment optimization has the potential to improve patient outcomes and reduce costs associated with inappropriate (or suboptimal) therapeutic regimens. Since a new technology may have additional initial cost, a policy question arises regarding whether the improvement in outcomes is attained at a 'reasonable' additional cost compared with existing technology. This paper presents an overview of health economic issues surrounding biomarkers in general, with a focus on cancer care and treatment optimization in particular. While this article is not a systematic review of the literature, it includes relevant examples to provide a real-world perspective.

References

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Citations

May 16, 2014·Molecular Diagnosis & Therapy·Maria Gazouli, Kyriakos Souliotis
Feb 28, 2015·Archives of Pathology & Laboratory Medicine·Timothy Craig Allen
Sep 4, 2015·Applied Health Economics and Health Policy·Marije OosterhoffLotte M G Steuten
Sep 4, 2015·Biomarkers in Medicine·Yinfa Ma, Sanjeewa Gamagedara
Apr 17, 2019·Journal of Food and Drug Analysis·Yi-Ting ChenYing-Hsu Chang
Sep 3, 2013·Archives of Pathology & Laboratory Medicine·Philip T CagleRandall J Olsen
Oct 19, 2016·The Journal of Urology·Joseph W McQuaid, Richard S Lee
Nov 16, 2019·Pharmaceutical Statistics·Daniele De Martini
Oct 22, 2016·New Biotechnology·Anne Blanchard

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Methods Mentioned

BETA
imaging techniques

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