Economics of gastroenteropancreatic neuroendocrine tumors: a systematic review

Therapeutic Advances in Endocrinology and Metabolism
Enrique GrandeMarta Trapero-Bertran

Abstract

Despite current interest, enthusiasm and progress in the development of therapies for gastroenteropancreatic (GEP) neuroendocrine tumors (NETs), there are substantial gaps in the published literature regarding cost-of-illness analyses, economic evaluation and budget impact analyses. Compounding the issue is that data on resource utilization and cost-effectiveness of different diagnostic and therapeutic modalities for GEP-NETs are scarce. A systematic review on the economic impact of GEP-NETs was carried out using four databases: EMBASE, PubMed, the National Health Service Economic Evaluation Database and Cochrane review. Fully published articles from January 2000 to May 2017, in English and Spanish, were included. All articles that satisfied the inclusion criteria were included in the systematic review; summary descriptive statistics were used to describe the methodological characteristics. The 14 studies selected included cost-of-illness analyses (n = 4), economic evaluations (n = 7) and budget impact analyses (n = 3). Almost all studies were performed in the United States. Healthcare costs for patients with NETs included medication, outpatient visits, hospitalizations, and check-ups/tests. Reducing adverse events is an area w...Continue Reading

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Citations

May 26, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Neal BhutianiRobert C G Martin
Nov 7, 2020·Reviews in Endocrine & Metabolic Disorders·B E WhiteJ K Ramage

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