Ecstasy use and self-reported depression, impulsivity, and sensation seeking: a prospective cohort study

Journal of Psychopharmacology
Maartje M L de WinWim van den Brink

Abstract

Although there are indications that ecstasy users have higher levels of depression, impulsivity, and sensation seeking, it is unknown whether these are consequences of ecstasy use or predisposing factors for starting ecstasy use. We prospectively assessed the predictive value of depression, impulsivity, and sensation seeking on future first time ecstasy use. We also assessed whether depression, impulsivity, and sensation seeking had changed after first ecstasy use. Depression, impulsivity, and sensation seeking were assessed using self-report questionnaires in 188 ecstasy-naive volunteers with high probability for future ecstasy use. After a mean follow-up of 17 months, measurements were repeated in 59 incident ecstasy users (mean 6.0 tablets) and 61 matched persistent ecstasy-naive volunteers. Only experience seeking (subscale of the sensation seeking scale) predicted future ecstasy use (OR -- 1.05, 95% CI 1.00 to 1.10), but after adjustment for potential confounders this was not significant anymore. At follow-up, significant effects of ecstasy use on the general and the disinhibition subscale of the sensation seeking scale were observed (after adjustment for potential confounders: regression coefficient B 0.51, 95% CI 0.20 to...Continue Reading

References

Feb 1, 1991·British Journal of Addiction·W Pedersen
Aug 1, 1968·Journal of Consulting and Clinical Psychology·M Zuckerman, K Link
Nov 1, 1984·Journal of Clinical Psychology·A T Beck, R A Steer
May 1, 1996·Behavioural Brain Research·M T BardoN G Harrington
Nov 1, 1995·Journal of Clinical Psychology·J H PattonE S Barratt
Jan 1, 1996·Neuropsychobiology·P NetterI S Roed
Nov 1, 1996·Progress in Neurobiology·Z CohenE Hamel
Aug 7, 1998·Biological Psychiatry·I Lucki
Aug 27, 1998·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·M J Morgan
Sep 19, 1998·European Addiction Research·P SchusterH U Wittchen
Dec 17, 1998·Neurology·K I BollaG A Ricaurte
Feb 13, 1999·International Clinical Psychopharmacology·G GerraR Delsignore
Jan 22, 2000·Neuroscience and Biobehavioral Reviews·A Meneses
Feb 23, 2000·Neuroreport·A GammaF X Vollenweider
May 2, 2000·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·F TuchtenhagenE Gouzoulis-Mayfrank
May 16, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·E Gouzoulis-MayfrankH Sass
May 24, 2000·Drug and Alcohol Dependence·A C ParrottJ J Turner
Jul 13, 2000·Addiction·W Pedersen, A Skrondal
Sep 18, 2002·Drug and Alcohol Dependence·Roselind LiebHans Wittchen
Oct 31, 2002·Human Psychopharmacology·Joerg DaumannEuphrosyne Gouzoulis-Mayfrank
Oct 31, 2002·Human Psychopharmacology·Giuliana DughieroGiovanni Forza
Oct 31, 2002·Human Psychopharmacology·A C ParrottJ Rodgers
Sep 19, 2003·Psychopharmacology·Alyson J BondH Valerie Curran
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Dec 9, 2003·Behavioural Brain Research·Tracie A PaineMary C Olmstead
Dec 23, 2003·Drug and Alcohol Dependence·Libby ToppLouisa Degenhardt

❮ Previous
Next ❯

Citations

Oct 25, 2006·Psychopharmacology·Casey R Guillot, Mitchell E Berman
Apr 18, 2009·Molecular Neurobiology·João Paulo CapelaFélix Carvalho
Feb 23, 2012·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nina Bl UrbanMarc Laruelle
Oct 10, 2008·Brain : a Journal of Neurology·Maartje M L de WinWim van den Brink
Jun 3, 2008·Journal of Psychopharmacology·L ClarkB J Sahakian
Oct 22, 2013·Psychopharmacology·Simon N YoungChawki Benkelfat
Nov 21, 2008·Psychopharmacology·Thelma SchiltBen Schmand
Apr 9, 2008·Substance Use & Misuse·Hylke K E VervaekeDirk J Korf
Jun 19, 2012·Addictive Behaviors·Irina MajumderRodney J Irvine
Sep 14, 2007·Drug and Alcohol Dependence·Rosa AlatiGail M Williams
Dec 25, 2010·Addiction·John E FiskFlorentia Hadjiefthyvoulou
Jan 3, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·M L J SchouwL Reneman
Feb 19, 2013·Journal of Affective Disorders·Michele FornaroSalvatore Colicchio
Jul 19, 2008·Journal of Psychopharmacology·K SoarJ Turner
Nov 2, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Maartje M L de WinWim van den Brink
Jul 23, 2015·Therapeutic Advances in Psychopharmacology·Rachel Patel, Daniel Titheradge
Dec 19, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Elisabeth M van de GiessenJan Booij
Jul 13, 2018·ACS Chemical Neuroscience·Lee E DunlapDavid E Olson

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