Ectoenzymes controlling leukocyte traffic

European Journal of Immunology
Marko Salmi, Sirpa Jalkanen

Abstract

Ectoenzymes are a diverse group of membrane proteins that have their catalytic sites outside the plasma membrane. Many of them are found on leukocytes and endothelial cells, and they are multifunctional in nature. Collectively, different ectoenzymes can modulate each step of leukocyte-endothelial contacts, as well as subsequent cell migration in tissues. Here, we review how ectoenzymes belonging to the oxidase, NAD-metabolizing enzyme, nucleotidase and peptidase/protease families regulate and fine-tune leukocyte trafficking, and how ectoenzymes have been targeted both in preclinical and clinical trials.

References

Mar 25, 2000·Journal of Leukocyte Biology·J W Goding
Jul 12, 2001·American Journal of Physiology. Gastrointestinal and Liver Physiology·K S KirkwoodE F Grady
Dec 19, 2001·Circulation·C GoepfertS Robson
Aug 18, 2004·Science·Kent W ChristophersonHal E Broxmeyer
Feb 1, 2005·The American Journal of Pathology·Nathalie BussoEric Grouzmann
Mar 4, 2005·The American Journal of Pathology·Marika MerinenSirpa Jalkanen
Oct 4, 2005·Nature Reviews. Immunology·Marko Salmi, Sirpa Jalkanen
Oct 4, 2005·Nature Reviews. Immunology·Ashley T Haase
Aug 22, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Yi-Guang ChenDavid V Serreze
Aug 24, 2006·The Journal of Biological Chemistry·Iliana MoreschiAntonio De Flora
Sep 2, 2006·Arthritis and Rheumatism·Fumiko Marttila-IchiharaMarko Salmi
Jan 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Patricia F LalorDavid H Adams
Mar 14, 2007·Circulation·Tobias EckleHolger K Eltzschig
Mar 21, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Vera PrellerDirk Reinhold
Aug 25, 2007·Nature Reviews. Immunology·Klaus LeySussan Nourshargh
Oct 20, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Kaisa KoskinenMarko Salmi
Nov 21, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Santiago Partida-SanchezFrances E Lund
Nov 23, 2007·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Kousuke NodaAli Hafezi-Moghadam
Nov 24, 2007·European Journal of Immunology·Jan KissMarko Salmi
Apr 12, 2008·Purinergic Signalling·Friedrich HaagFriedrich Koch-Nolte
Sep 27, 2008·The American Journal of Pathology·Tae NakasakiMasayuki Miyasaka
Oct 1, 2008·European Journal of Immunology·Jussi NiemeläLaura Airas
Oct 8, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Jörg ReutershanHolger K Eltzschig
Feb 24, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Felix ScheupleinFriedrich Koch-Nolte
Apr 22, 2009·The Journal of Clinical Investigation·Matthew C HymanDavid J Pinsky

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Citations

Jan 19, 2013·Journal of Neural Transmission·Eva Bligt-LindénTiina Annamaria Salminen
Dec 7, 2013·Journal of Medicinal Chemistry·Eva Bligt-LindénTiina A Salminen
Mar 19, 2014·Seminars in Immunopathology·Marko Salmi, Sirpa Jalkanen
Apr 23, 2014·The Journal of Biological Chemistry·Simona MoroneAda Funaro
Feb 26, 2015·American Journal of Physiology. Endocrinology and Metabolism·Ping HuMaria B Grant
Apr 13, 2013·European Journal of Immunology·Jason W Griffith, Andrew D Luster
Jun 22, 2013·European Journal of Immunology·Reinhold Förster, Silvano Sozzani
Mar 18, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Serhii VakalTiina A Salminen

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