Ectopic pregnancy: an update

Current Opinion in Obstetrics & Gynecology
Martin C Sowter, Cindy M Farquhar

Abstract

This review discusses recent publications that investigate the epidemiology, diagnosis and treatment of ectopic pregnancy. Transvaginal ultrasound is being used with increasing confidence for the diagnosis of ectopic pregnancy, and methotrexate now has an established role in the treatment of ectopic pregnancy. No serum markers have been found that can reliably differentiate intrauterine from extrauterine pregnancy. As more experience has been gained with medical therapy, it is apparent that it is possible to identify a subgroup of women in whom it is unlikely to succeed. The use of adjunctive therapy such as mifepristone does not appear to increase the effectiveness of methotrexate. Screening for ectopic pregnancy in at-risk women has been suggested, but it may be of only limited value. In the surgical management of ectopic pregnancy the effect on fertility of salpingotomy and salpingectomy remains uncertain, although recent cohort studies suggest that salpingotomy may be associated with a better subsequent intrauterine pregnancy rate than salpingectomy. A number of case reports of pregnancies at unusual sites continue to be published, but in the last 2 years there has been a dramatic increase in the number of caesarean scar pr...Continue Reading

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Mar 11, 2010·Current Opinion in Obstetrics & Gynecology·Hye Jin Chang, Chang Suk Suh
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Sep 10, 2008·Expert Opinion on Pharmacotherapy·Giuseppe BenagianoManuela Farris

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