Eczema herpeticum in children: clinical features and factors predictive of hospitalization

The Journal of Pediatrics
Nadia Jennifer Chiara LucaElena Pope

Abstract

To describe the clinical characteristics of pediatric patients with eczema herpeticum and to determine the predictors of hospitalization, and recurrence and repeat episodes. A retrospective cohort study of patients 0-18 years of age diagnosed with eczema herpeticum between May 2000 and April 2009 was carried out at a tertiary pediatric care center in Canada. Seventy-nine patients were included. The primary outcome was hospitalization; secondary outcomes were recurrent and repeat episodes of eczema herpeticum. At presentation, 76% of 79 patients with eczema herpeticum had a generalized eruption, 56% had fever, 37% had systemic symptoms, and 10% had eye involvement (keratoconjunctivitis). Forty-five patients (57%) were hospitalized. Predictors for hospitalization included male sex (OR = 3.09; 95% CI, 1.20-7.95, P = .017), fever (OR = 5.75; 95% CI, 2.17-15.26, P < .001), systemic symptoms (OR = 2.84; 95% CI, 1.06-7.62, P = .035), and age <1 year (OR = 7.17; 95% CI, 2.17-23.72, P = .001). Recurrence rate (<1 month) was 8.9% and rate of repeat episodes (>1 month) was 16%. Hospitalized patients were more likely to have a repeat episode (OR = 8.25; 95% CI, 0.99-68.69, P = .05). Patients with a previous history of eczema herpeticum had...Continue Reading

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May 12, 2012·The Journal of Pediatrics·Nadia Jennifer Chiara LucaElena Pope

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Citations

Mar 19, 2014·Pediatric Clinics of North America·Sierra Wolter, Harper N Price
Apr 25, 2013·The Journal of Allergy and Clinical Immunology·David H Dreyfus
Mar 5, 2016·Italian Journal of Pediatrics·Elena GalliLawrence F Eichenfield
May 12, 2012·The Journal of Pediatrics·Nadia Jennifer Chiara LucaElena Pope
Jun 22, 2017·Pediatric Dermatology·Julia K GittlerSeth J Orlow
Nov 17, 2015·The Pediatric Infectious Disease Journal·Laila F IbrahimPenelope A Bryant
Jul 3, 2016·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Christina L TupeMichael T McCurdy
Jan 3, 2014·International Journal of Rheumatic Diseases·Amal Bakry Abdul-SattarMohamed G Negm
Apr 9, 2019·Global Pediatric Health·Ali OzcanDan Nguyen
Aug 5, 2015·Pediatric Emergency Care·Maximilian BlanterBijan Safai
Sep 16, 2017·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M TheilerL Weibel

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