Edaravone inhibits the disease activity in rheumatoid arthritis

Journal of Clinical Pharmacy and Therapeutics
Kaoru AriiKozo Hashimoto

Abstract

A male patient with rheumatoid arthritis (RA) developed acute stroke and was treated with the free radical scavenger, edaravone. Polyarthralgia improved with a reduction in serum C-reactive protein concentration soon after the start of edaravone administration. The disease activity score 28 (DAS28) also decreased. Edaravone appears to be effective for the control of RA. The usefulness of this potentially novel therapeutic agent should be tested in a well designed randomized controlled trial.

References

Jan 29, 2000·Rheumatology International·H S OztürkI Durak
Feb 13, 2003·American Journal of Epidemiology·James R CerhanLindsey A Criswell
Jun 11, 2003·Journal of Gastroenterology and Hepatology·Shinchiro TadaHiromasa Ishii
Jun 12, 2004·Free Radical Research·Taro IguchiMasayasu Inoue
Jan 5, 2006·Free Radical Research·Kaoru AriiKozo Hashimoto

❮ Previous
Next ❯

Citations

Jan 18, 2013·Neurotoxicity Research·Yue-E ShenLi-Ming Zhang
Apr 6, 2011·Journal of Clinical Pharmacy and Therapeutics·H KawashimaY Watanabe
Jun 4, 2008·Biological & Pharmaceutical Bulletin·Toshiaki SatoFumiyoshi Ishii
Jul 9, 2008·Acta Oto-laryngologica·Monika Stenkvist AsplundMatti Anniko
Mar 30, 2016·Human & Experimental Toxicology·M TuranK Önal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.