Editorial: Increasing Incidence of Pediatric Inflammatory Bowel Disease in France: Implications for Etiology, Diagnosis, Prognosis, and Treatment

The American Journal of Gastroenterology
Edward L Barnes, Michael D Kappelman

Abstract

The significant increase in pediatric-onset inflammatory bowel disease in recent decades appears to be a global phenomenon, with studies from multiple geographic areas noting an increase in Crohn's disease (CD) and ulcerative colitis (UC). In this large, population-based cohort from northern France, the rapid increase in pediatric CD and UC from 1988-2011 may be due to multiple potential etiologies including environmental factors and advancements in diagnostic capabilities. We should consider the clinical implications of this rise in incidence, including potential risk stratification approaches that may offer the ability to modify the disease course of patients with earlier diagnosis.

References

Jun 22, 2010·Inflammatory Bowel Diseases·Eric I BenchimolAnne M Griffiths
Oct 23, 2010·Gut·Anders HviidMorten Frisch
Apr 22, 2011·Inflammatory Bowel Diseases·Stephan R VavrickaUNKNOWN Swiss IBD Cohort Study Group
Jun 21, 2011·Inflammatory Bowel Diseases·Paul HendersonDavid C Wilson
Sep 14, 2011·The American Journal of Gastroenterology·Souradet Y ShawCharles N Bernstein
May 3, 2012·Archives of Disease in Childhood·B HopeB Bourke
Jan 24, 2013·Inflammatory Bowel Diseases·Xin-qiong WangXiao-jin Wang
Mar 6, 2013·Journal of Pediatric Gastroenterology and Nutrition·Petter MalmborgHans Hildebrand
May 3, 2014·Inflammatory Bowel Diseases·Mohammad I El MouzanSami Wali
Mar 11, 2015·The American Journal of Gastroenterology·Eric I BenchimolDouglas G Manuel
Jun 17, 2016·Journal of Pediatric Gastroenterology and Nutrition·Caterina StrisciuglioErasmo Miele
Aug 3, 2016·Inflammatory Bowel Diseases·Aurada Cholapranee, Ashwin N Ananthakrishnan

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