Educational program for nursing home physicians and staff to reduce use of non-steroidal anti-inflammatory drugs among nursing home residents: a randomized controlled trial

Medical Care
C M SteinW A Ray

Abstract

The risk for serious gastrointestinal complications due to nonsteroidal anti-inflammatory drugs (NSAIDs) is high in the elderly. Acetaminophen-based regimens are safer and may be as effective as NSAIDs for the treatment of osteoarthritis in many patients. To determine the effects of an educational program on NSAID use and clinical outcomes in nursing homes. Randomized controlled study. Ten pairs of Tennessee nursing homes with > or = 8% of residents receiving NSAIDs were randomized to intervention or control. Nursing home residents (intervention n = 76 and control n = 71) aged 65 years and older taking NSAIDs regularly. An educational program for physicians and nursing home staff that included the risks and benefits of NSAIDs in the elderly and an algorithm that substituted acetaminophen, topical agents, and nonpharmacologic measures for the treatment of noninflammatory musculoskeletal pain. Intervention and control subjects were assessed at baseline and 3 months later. Differences in NSAID and acetaminophen use, and pain, function, and disability scores in intervention and control nursing home subjects. The intervention was effective resulting in markedly decreased NSAID use and increased acetaminophen use. Mean number of days...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jan 1, 1992·British Journal of Rheumatology·A C JonesM Doherty
Sep 1, 1991·The American Journal of Medicine·J F FriesB A Michel
Apr 1, 1990·Journal of the American Geriatrics Society·B A FerrellD Osterweil
Jan 1, 1990·Health Affairs·W A RayR I Shorr
Nov 1, 1990·Mayo Clinic Proceedings·N J TalleyL J Melton
Nov 1, 1995·Annals of Internal Medicine·B A Ferrell
Nov 1, 1995·Journal of Pain and Symptom Management·B A FerrellL Rivera
Aug 1, 1996·Journal of General Internal Medicine·W E SmalleyW A Ray
May 8, 1998·The American Journal of Medicine·M R Griffin
Aug 26, 1998·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Feb 3, 1999·Lancet·C J Hawkey

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Citations

Mar 12, 2013·Drugs & Aging·Jennifer TjiaBecky A Briesacher
Oct 18, 2002·Journal of the American Geriatrics Society·Sarah MeredithWayne A Ray
Oct 18, 2002·Journal of the American Geriatrics Society·Peter A Boling
Jan 26, 2011·Age and Ageing·Mathumalar LoganathanAzeem Majeed
Apr 5, 2003·The Gerontologist·Sandra AylwardVan Johncox
Jan 15, 2004·Annals of the Rheumatic Diseases·K D Brandt
Feb 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lona ModySarah L Krein
Apr 21, 2012·Obstetrics and Gynecology International·Archana DixitBhavna Sharma
Jun 27, 2012·BMC Geriatrics·Adam L GordonUNKNOWN Medical Crises in Older People Study Group
Jul 1, 2008·Research in Gerontological Nursing·Meg Bourbonniere, Neville E Strumpf
Nov 30, 2006·Worldviews on Evidence-based Nursing·Katherine R JonesB Karen Mellis
Jun 30, 2009·Journal of the American Geriatrics Society·Adam D HermanPatricia A Parmelee
Apr 17, 2004·Journal of the American Geriatrics Society·Karen S Feldt
Jun 16, 2010·Journal of Evaluation in Clinical Practice·Svetlana Vladislavovna DoubovaRicardo Pérez-Cuevas
Feb 6, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Kurt B Stevenson, Mark Loeb
May 13, 2014·Journal of the American Medical Directors Association·Kaisu H PitkäläMikko Björkman
Nov 26, 2016·Journal of the American Medical Directors Association·Jennifer A Knopp-SihotaCarole A Estabrooks
Dec 17, 2015·Therapeutic Advances in Drug Safety·Doron GarfinkelGulistan Bahat
Apr 11, 2012·Nature Reviews. Neurology·Anne CorbettClive Ballard
Jun 4, 2008·Medical Care·Aaron W CalhounAdrienne G Randolph
Oct 18, 2006·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Steven A MazzucaPatricia M Gʼsell
May 31, 2012·Drugs & Aging·Marie N O'ConnorDenis O'Mahony
Feb 14, 2021·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Joshua M PevnickJeffrey L Schnipper
Sep 16, 2021·The Cochrane Database of Systematic Reviews·Louise ForsetlundChristopher J Rose

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