EEG features in idiopathic generalized epilepsy: clues to diagnosis

Epilepsia
Luiz Eduardo BettingFernando Cendes

Abstract

To investigate the EEG profile and its contribution for diagnosis and management in a group of patients with a clinical diagnosis of idiopathic generalized epilepsy (IGE) who were referred to a tertiary hospital. We retrospectively studied clinical and EEG features of 180 consecutive patients with IGE. Eighty patients were diagnosed with juvenile myoclonic epilepsy (JME), 35 had absence epilepsy (AE), 13 had generalized tonic-clonic seizures on awakening (GTCS-A), 28 had generalized tonic-clonic seizures only (TCS), and 24 had adult-onset idiopathic generalized epilepsy (AIGE). The EEGs were classified in typical (synchronous generalized spike or polyspikes-and-wave discharges with normal background), atypical (with clear focalities or asymmetries), and normal. The 493 EEG exams were analyzed. The first EEG was normal in 45% of the 180 patients, and only 33% had typical abnormalities. AE had a higher proportion of typical examinations and needed fewer sequential examinations to register a typical abnormality compared with the other groups. By contrast, the serial EEG profile of TCS and AIGE showed a higher proportion of normal and atypical EEG findings. These findings support previous recommendations that IGE patients should be...Continue Reading

References

Mar 1, 1988·Epilepsy Research·L GramM Dam
Aug 1, 1971·Electroencephalography and Clinical Neurophysiology·K A KooiR E Marshall
Nov 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·C D Binnie, P F Prior
Mar 1, 1994·Epilepsia·M E LancmanJ K Penry
Jan 4, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·C P PanayiotopoulosA Agathonikou
Apr 8, 1998·Acta Neurologica Scandinavica·S B Pedersen, K A Petersen
Apr 21, 1998·Seizure : the Journal of the British Epilepsy Association·J M MurthyA K Meena
Jan 15, 1999·Seizure : the Journal of the British Epilepsy Association·J LoiseauP Loiseau
Sep 21, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·D Janz
Nov 18, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·M Manford
Aug 30, 2002·Epilepsy Research·Fritz LeutmezerChristoph Baumgartner
Jan 18, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·C MariniS F Berkovic
Feb 1, 2003·Epilepsia·Suthida YenjunSamuel F Berkovic

❮ Previous
Next ❯

Citations

Oct 8, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ioannis KarakisAndrew J Cole
Jan 21, 2010·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Bernhard OehlAndreas Schulze-Bonhage
May 28, 2010·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·William O TatumSelim R Benbadis
Aug 23, 2006·Epilepsia·Christine WhylingsSanjeev V Kothare
Mar 14, 2013·SpringerPlus·Rajib Nayan ChowdhuryQuazi Deen Mohammad
Dec 30, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Giorgi JaparidzeSándor Beniczky
Dec 6, 2014·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ali A Asadi-PooyaMehrdad Emami
Jun 17, 2015·Seizure : the Journal of the British Epilepsy Association·Konrad J WerhahnSoheyl Noachtar
Mar 6, 2008·Clinical EEG and Neuroscience·F Irsel TezerSerap Saygi
Sep 23, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L NobiliL Vignatelli
Oct 11, 2017·Frontiers in Neurology·Udaya SeneviratneWendyl Jude D'Souza
Nov 10, 2010·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Karine LétourneauCharles Deacon
Feb 22, 2021·Epilepsy & Behavior : E&B·Jacopo C DiFrancescoCarlo Ferrarese
Feb 21, 2021·Seizure : the Journal of the British Epilepsy Association·Mariana R BritoFernando Cendes
Nov 15, 2012·Journal of the Neurological Sciences·Ali A Asadi-PooyaMichael R Sperling

❮ Previous
Next ❯

Related Concepts

Related Feeds

Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.