Eel electric organ: hyperexpressing calmodulin system.

Molecular and Cellular Biology
R P MunjaalJ R Dedman

Abstract

The electroplax of the electric eel Electrophorus electricus is the most abundant source of the calcium-binding protein calmodulin. The electroplax has 250 times the amount of calmodulin and its mRNA than eel skeletal muscle. Our data suggest that there is no major difference in gene copies, the degree of methylation, or genome rearrangement of the calmodulin gene in DNAs from eel electroplax and muscle. Differences in the calmodulin-binding proteins in electroplax and muscle suggest a differential role for the functional expression of calmodulin in cellular regulation.

References

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Citations

Mar 20, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·A L GotterJ R Dedman
Sep 1, 1997·Comparative Biochemistry and Physiology. Part A, Physiology·A L GotterJ R Dedman

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