Effect modification of ambient particle mortality by radon: A time series analysis in 108 U.S. cities

Journal of the Air & Waste Management Association
Annelise J BlombergPetros Koutrakis

Abstract

Numerous studies have reported a positive association between ambient fine particles and daily mortality, but little is known about the particle properties or environmental factors that may contribute to these effects. This study assessed potential modification of radon on PM2.5 (particulate matter with an aerodynamic diameter <2.5 μm)-associated daily mortality in 108 U.S. cities using a two-stage statistical approach. First, city- and season-specific PM2.5 mortality risks were estimated using over-dispersed Poisson regression models. These PM2.5 effect estimates were then regressed against mean city-level residential radon concentrations to estimate overall PM2.5 effects and potential modification by radon. Radon exposure estimates based on measured short-term basement concentrations and modeled long-term living-area concentrations were both assessed. Exposure to PM2.5 was associated with total, cardiovascular, and respiratory mortality in both the spring and the fall. In addition, higher mean city-level radon concentrations increased PM2.5-associated mortality in the spring and fall. For example, a 10 µg/m3 increase in PM2.5 in the spring at the 10th percentile of city-averaged short-term radon concentrations (21.1 Bq/m3) wa...Continue Reading

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Citations

Sep 13, 2019·Environmental Health : a Global Access Science Source·Carolina Leticia Zilli VieiraPetros Koutrakis
Jan 6, 2021·Environment International·Stefania PapatheodorouPetros Koutrakis
Dec 18, 2020·Toxics·Anna Grzywa-CelińskaKrzysztof Kozak
Nov 18, 2020·Journal of the Air & Waste Management Association·Joy LawrencePetros Koutrakis
Apr 21, 2021·Environmental Monitoring and Assessment·Caleb AdeoyeAtin Adhikari

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