Effect of 2-hydroxy-4-(methylthio) butanoic acid and acidifier on the performance, chyme pH, and microbiota of broilers

Animal Science Journal = Nihon Chikusan Gakkaihō
Yuqin WuJianmin Yuan

Abstract

This study was aimed to explore the comparative acidifying properties of 2-hydroxy-4-(methylthio) butanoic acid (HMTBA) and a combination of DL-methionine (DLM) and acidifier in male broiler production. A total of 480 1-day-old broiler chicks were randomly divided into four treatments: A (low HMTBA, 0.057% HMTBA); B (low acidifier, 0.05% DLM + 0.057% acidifier); C (high HMTBA, 0.284% HMTBA); and D (high acidifier, 0.25% DLM + 0.284% acidifier). At 21 d, growth performance, chyme pH, digestive enzyme activities, and intestinal microflora were measured. The pH of crop, gizzard, and ileum contents was higher in the HMTBA treatment group than in DLM + acidifier treatment group. Furthermore, acidifier supplementation promoted growth of butyrate-producing bacteria such as Faecalibacterium, whereas high HMTBA (0.284%) inhibited the proliferation of acid-producing bacteria including Roseburia and Collinsella. The chymotrypsin activity was lower in the HMTBA group than in the DLM + acidifier group. In contrast, high-level HMTBA group showed higher average daily gain and average daily feed intake than the DLM + acidifier group. These results suggested that HMTBA work through different pathways with DLM plus acidifier.

References

Jun 26, 2007·Applied and Environmental Microbiology·Qiong WangJames R Cole
Nov 23, 2007·Archives of Animal Nutrition·Habib Ur RehmanJürgen Zentek
Apr 4, 2008·Proceedings of the National Academy of Sciences of the United States of America·Uttam L RajBhandary, Dieter Söll
Apr 13, 2010·Nature Methods·J Gregory CaporasoRob Knight
Mar 3, 2011·MBio·Sandrine P ClausJeremy K Nicholson
Jun 28, 2011·Genome Biology·Nicola SegataCurtis Huttenhower
Feb 16, 2012·BMC Bioinformatics·Andre P MasellaJosh D Neufeld
Aug 27, 2013·Nature Biotechnology·Morgan G I LangilleCurtis Huttenhower
Sep 24, 2015·Nature Communications·Jon G SandersPeter R Girguis
Dec 4, 2015·Archives of Animal Nutrition·Ellen ZellerMarkus Rodehutscord

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