Effect of a Bayesian Penalized Likelihood PET Reconstruction Compared With Ordered Subset Expectation Maximization on Clinical Image Quality Over a Wide Range of Patient Weights

AJR. American Journal of Roentgenology
Anna K ChilcottDaniel R McGowan

Abstract

A study was performed to compare background liver signal-to-noise ratio (SNR) and visually assessed image quality of clinical PET/CT studies from the same PET acquisition data reconstructed by Bayesian penalized likelihood (BPL) and ordered subset expectation maximization (OSEM) over a range of patient weights. The effect of a BPL PET reconstruction algorithm on liver SNR and visually assessed image quality over a range of patient weights (41-196 kg; n = 108) was retrospectively compared with standard-of-care OSEM reconstruction on the same PET acquisition data after IV administration of 18F-FDG (4 MBq/kg). BPL showed no significant change (p > 0.05) in liver SNR with increasing weight and body mass index (BMI), whereas OSEM showed increasing noise with increasing weight and BMI. The liver SNR was significantly higher using BPL than a standard OSEM reconstruction (p < 0.0002 for all BMI groups). Visually assessed image quality declined at a greater rate with increasing weight and BMI in the OSEM images than with BPL images. BPL provides a more consistent visually assessed image quality and liver background SNR than does OSEM, with the greatest benefit for the heaviest patients.

References

Dec 17, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Mitsuaki TatsumiRichard L Wahl
Jul 9, 2003·IEEE Transactions on Medical Imaging·Sangtae Ahn, Jeffrey A Fessler
Aug 14, 2013·EJNMMI Research·Eleonore H de GrootJorn A van Dalen
Dec 3, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Ronald BoellaardUNKNOWN European Association of Nuclear Medicine (EANM)
Jul 15, 2015·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Eugene J TeohFergus V Gleeson

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Citations

Jun 25, 2019·Nuclear Medicine and Molecular Imaging·Antonella MattiStefano Fanti
Apr 28, 2018·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Kevin M BradleyAndrei H Iagaru
Jun 4, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Nicolas AideDaniel R McGowan

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