Effect of a chronic GSM 900 MHz exposure on glia in the rat brain

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Mohamed AmmariRené de Seze

Abstract

Extension of the mobile phone technology raises concern about the health effects of 900 MHz microwaves on the central nervous system (CNS). In this study we measured GFAP expression using immunocytochemistry method, to evaluate glial evolution 10 days after a chronic exposure (5 days a week for 24 weeks) to GSM signal for 45 min/day at a brain-averaged specific absorption rate (SAR)=1.5 W/kg and for 15 min/day at a SAR=6 W/kg in the following rat brain areas: prefrontal cortex (PfCx), caudate putamen (Cpu), lateral globus pallidus of striatum (LGP), dentate gyrus of hippocampus (DG) and cerebellum cortex (CCx). In comparison to sham or cage control animals, rats exposed to chronic GSM signal at 6 W/kg have increased GFAP stained surface areas in the brain (p<0.05). But the chronic exposure to GSM at 1.5 W/kg did not increase GFAP expression. Our results indicated that chronic exposure to GSM 900 MHz microwaves (SAR=6 W/kg) may induce persistent astroglia activation in the rat brain (sign of a potential gliosis).

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Citations

Nov 27, 2009·International Journal of Impotence Research·N SalamaS Kagawa
Feb 5, 2010·Pakistan Journal of Biological Sciences : PJBS·S S Mazloomy MahmoodabadM T Yavari
Jun 21, 2013·Electromagnetic Biology and Medicine·Daryoush Shahbazi-GahroueiMilad Baradaran-Ghahfarokhi
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Apr 20, 2010·International Journal of Radiation Biology·Mohamed AmmariRené De Seze
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Oct 4, 2016·Environmental Science and Pollution Research International·Amélie BarthélémyAnne-Sophie Villégier
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Jun 26, 2018·International Journal of Radiation Biology·Enis HidisogluPiraye Yargicoglu
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Feb 19, 2021·Military Medical Research·Yun-Fei LaiRui-Yun Peng
Jun 3, 2021·International Journal of Molecular Sciences·Haifa OthmanElena López-Martín

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