Effect of a comprehensive programme to provide universal access to care for sputum-smear-positive multidrug-resistant tuberculosis in China: a before-and-after study

The Lancet Global Health
Renzhong LiDaniel P Chin

Abstract

China has a quarter of all patients with multidrug-resistant tuberculosis (MDRTB) worldwide, but less than 5% are in quality treatment programmes. In a before-and-after study we aimed to assess the effect of a comprehensive programme to provide universal access to diagnosis, treatment, and follow-up for MDRTB in four Chinese cities (population 18 million). We designated city-level hospitals in each city to diagnose and treat MDRTB. All patients with smear-positive pulmonary tuberculosis diagnosed in Center for Disease Control (CDC) clinics and hospitals were tested for MDRTB with molecular and conventional drug susceptibility tests. Patients were treated with a 24 month treatment package for MDRTB based on WHO guidelines. Outpatients were referred to the CDC for directly observed therapy. We capped total treatment package cost at US$4644. Insurance reimbursement and project subsidies limited patients' expenses to 10% of charges for services within the package. We compared data from a 12 month programme period (2011) to those from a retrospective survey of all patients with MDRTB diagnosed in the same cities during a baseline period (2006-09). 243 patients were diagnosed with MDRTB or rifampicin-resistant tuberculosis during the...Continue Reading

References

Feb 28, 2009·The Lancet Infectious Diseases·Evan W OrensteinAlison P Galvani
May 22, 2009·BMC Infectious Diseases·Freddie BwangaMoses L Joloba
Oct 17, 2009·American Journal of Respiratory and Critical Care Medicine·Neel R GandhiUNKNOWN Tugela Ferry Care and Research (TF CARES) Collaboration
Oct 1, 2008·Expert Review of Respiratory Medicine·Daphne I LingMadhukar Pai
Sep 10, 2010·The New England Journal of Medicine·Eva NathansonMario Raviglione
Mar 24, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Guang Xue HeMartien W Borgdorff
Jun 15, 2011·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·J FurinS Shin
Aug 11, 2011·The European Respiratory Journal·D FalzonM Zignol
Jan 13, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·Greg Jonsson, Jennifer Furin
Mar 6, 2012·Lancet·Winnie Chi-Man YipAlan Maynard
Apr 6, 2012·The Journal of Infectious Diseases·Alimuddin ZumlaRifat Atun
Jun 8, 2012·The New England Journal of Medicine·Yanlin ZhaoYu Wang
Jun 14, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·J S CavanaughJ P Cegielski
Aug 7, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·M T GlerT E Tupasi
Sep 7, 2012·PLoS Medicine·Shama D AhujaUNKNOWN Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB
Sep 11, 2012·Lancet·William D SavedoffVictoria Fan
Oct 13, 2012·The European Respiratory Journal·G B MiglioriUNKNOWN “The Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB”
Oct 24, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Karen R JacobsonRobin M Warren
Oct 27, 2012·The European Respiratory Journal·Dennis FalzonUNKNOWN Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB
Dec 6, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·A ToczekN Ford
Mar 22, 2013·Journal of Clinical Microbiology·Yu PangYanlin Zhao
Jun 8, 2013·The Lancet Infectious Diseases·Dennis FalzonMario C Raviglione
Jul 6, 2013·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·J I EbonwuC Ihekweazu
Aug 9, 2013·The American Journal of Tropical Medicine and Hygiene·Amal BassiliErnesto Jaramillo
Dec 7, 2013·Lancet·Dean T JamisonGavin Yamey
Jan 23, 2014·The Cochrane Database of Systematic Reviews·Karen R SteingartNandini Dendukuri

❮ Previous
Next ❯

Citations

Feb 18, 2016·Transactions of the Royal Society of Tropical Medicine and Hygiene·Derek J Sloan, Joseph M Lewis
Mar 22, 2015·The Lancet Global Health·Karen R Jacobson, Lora L Sabin
Jan 30, 2016·Infectious Diseases of Poverty·Shenglan TangDaniel P Chin
Jan 26, 2016·Infectious Diseases of Poverty·Chengchao ZhouHenry Lucas
Jan 30, 2016·Infectious Diseases of Poverty·Qian LongHenry Lucas
Mar 30, 2019·Transboundary and Emerging Diseases·Kefyalew Addis AleneArchie C A Clements
Jan 20, 2018·Transactions of the Royal Society of Tropical Medicine and Hygiene·Myat K ThuSi T Aung
Jul 25, 2019·International Journal of Environmental Research and Public Health·Junnan JiangShenglan Tang
Nov 10, 2015·Bulletin of the World Health Organization·Christopher FitzpatrickKatherine Floyd

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Related Papers

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
H-B XuH-P Xiao
Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace
M La RajaE Pitzus
© 2021 Meta ULC. All rights reserved