Effect of a course of electroconvulsive therapy on interictal bispectral index values: a prospective study

The Journal of ECT
Rohini ThimmaiahGanne S Umamaheshwara Rao

Abstract

Bispectral index (BIS) value measures the level of hypnosis (sedation) during anesthesia. It uses electroencephalographic signals to measure the level of sedation. Electroconvulsive therapy (ECT)-induced changes in electroencephalography last for several hours to days. How this affects BIS values is unknown. In 30 patients with schizophrenia or mood disorders who were prescribed ECT (bitemporal, brief-pulse ECT), BIS values were obtained before the start of anesthesia on the first (baseline), fourth (48 hours after the third ECT), and seventh ECT (48 hours after the sixth ECT) sessions. Bispectral index values were recorded in resting state and during a short conversation a few minutes before the induction of anesthesia. The changes in BIS values through the course of ECT were analyzed using repeated-measures analysis of variance and the McNemar test. Mean (SD) resting BIS value dropped from 91.6 (6.6) at baseline to 79.7 (20.2) after the sixth ECT (repeated-measures analysis of variance occasion effect: F = 6.78; df = 2,58; P = 0.02). The drop in corresponding values during conversation was not significant. The proportion of patients whose resting BIS values were in the sedated/anesthetized range increased from 26% at baseline...Continue Reading

Citations

Nov 30, 2013·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Per Bergsholm
Oct 11, 2015·Brain Stimulation·Verònica GálvezColleen K Loo
May 4, 2017·Acta Neuropsychiatrica·Tobias Kvist StrippNiels Vidiendal Olsen
Jun 6, 2018·Frontiers in Psychiatry·Ben J A PalancaMichael S Avidan
Jun 1, 2019·Journal of Clinical Anesthesia·Gilles Guerrier, Marc-Antoine Gianni
Feb 8, 2020·Psychiatry Research·Kasra ZareiGen Shinozaki

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.