PMID: 1207285Jan 1, 1975Paper

Effect of a decrease in viscosity on myocardial blood flow and function in myocardial infarct

Langenbecks Archiv für Chirurgie
C HottenrottJ V Maloney

Abstract

In 5 dogs the effect of a decrease in blood viscosity on myocardial blood flow (radioactive microspheres) and left ventricular function (Sarnoff curves) following ligation of the left anterior descending coronary artery was tested. Moderate anaemia produced a significant increase in coronary blood flow to the total left ventricle (+ 100%) and to the ischemic area (+ 400%). Depressed left ventricular function after coronary ligation alone was restored when blood viscosity was lowered only slightly. Severe anaemia further increased coronary blood flow but left ventricular function worsened.

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