Effect of a dietary supplement on peri-implant bone strength in a rat model of osteoporosis

Journal of Prosthodontic Research
Takahiro TakahashiYasuhiko Kawai

Abstract

Osteoporosis contributes to impaired bone regeneration and remodeling through an imbalance of osteoblastic and osteoclastic activity, and can delay peri-implant bone formation after dental implant surgery, resulting in a prolonged treatment period. It poses several difficulties for individuals with large edentulous areas, and decreases their quality of life. Consequently, prompt postoperative placement of the final prosthesis is very important clinically. Peri-implant bone formation may be enhanced by systemic approaches, such as the use of osteoporosis supplements, to promote bone metabolism. We aimed to confirm whether intake of synthetic bone mineral (SBM), a supplement developed for osteoporosis, could effectively accelerate peri-implant bone formation in a rat model of osteoporosis. Thirty-six 7-week-old ovariectomized female Wistar rats were randomly assigned to receive a standardized diet with or without SBM (Diet with SBM group and Diet without SBM group, respectively; n=18 for both). The rats underwent implant surgery at 9 weeks of age under general anesthesia. The main outcome measures, bone mineral density (BMD) and pull-out strength of the implant from the femur, were compared at 2 and 4 weeks after implantation usi...Continue Reading

References

Feb 1, 1996·International Journal of Oral and Maxillofacial Surgery·J E BlomqvistB G Hansson
Aug 13, 2004·Journal of Biomedical Materials Research. Part a·Miho InoueNoriyuki Nagai
Oct 30, 2004·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·M FiniA Carpi
Dec 21, 2004·The Journal of Nutritional Biochemistry·Robert K Rude, Helen E Gruber
Dec 3, 2005·The Journal of Clinical Investigation·Lawrence G Raisz
Jul 10, 2007·Journal of Biomedical Materials Research. Part a·Yasutaka YamadaRacquel Z LeGeros
Nov 6, 2009·Journal of Oral Rehabilitation·Y AyukawaK Koyano
Nov 4, 2010·Clinical Oral Implants Research·Toru OgawaJoke Duyck
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Conrado AparicioFrancisco-Javier Gil
Dec 4, 2012·Archives of Osteoporosis·Hajime OrimoSaeko Fujiwara
Sep 24, 2013·Journal of Dental Research·H S AlghamdiJ A Jansen
Dec 26, 2013·BioMed Research International·Giovanna ZacchettiPatrick Ammann
Jan 24, 2014·The International Journal of Oral & Maxillofacial Implants·Takahiro Ogawa
Dec 23, 2014·Journal of Prosthodontic Research·Yo Shibata, Yasuhiro Tanimoto
May 23, 2015·Healthcare Informatics Research·Il Kon Kim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
F-F ChouK-Y Lu
Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
J YinS Kadota
© 2022 Meta ULC. All rights reserved