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Effect of a hepatic activation system on the antiproliferative activity of hexamethylmelamine against human tumor cell lines

Cancer Chemotherapy and Pharmacology

Jan 1, 1985

Kenneth W MillerMatthew M Ames

PMID: 3924426

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Abstract

Incubation of hexamethylmelamine for 1 h with human tumor cell lines in culture did not inhibit colony formation at concentrations up to the limit of drug solubility (200 micrograms/ml). When 1-h incubations were carried out in the presence of a 9,000 g rat liver supernatant preparation...read more

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Mutamycin
DNA, A-Form
Supernatant
NADP
Cyclophosphamide
Hexinawas
Metabolic Inhibition
Lung Problem
Structure of Parenchyma of Lung
Entire Lung
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Effect of a hepatic activation system on the antiproliferative activity of hexamethylmelamine against human tumor cell lines

Cancer Chemotherapy and Pharmacology

Jan 1, 1985

Kenneth W MillerMatthew M Ames

PMID: 3924426

DOI:

Abstract

Incubation of hexamethylmelamine for 1 h with human tumor cell lines in culture did not inhibit colony formation at concentrations up to the limit of drug solubility (200 micrograms/ml). When 1-h incubations were carried out in the presence of a 9,000 g rat liver supernatant preparation...read more

Mentioned in this Paper

Mutamycin
DNA, A-Form
Supernatant
NADP
Cyclophosphamide

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Paper Details
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