Effect of a high and low dose of caffeine on human lymphocyte activation in response to antigen stimulation

Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme
Deborah K Dulson, Nicolette C Bishop

Abstract

This study investigated the effect of caffeine on antigen-stimulated lymphocyte activation. Six males rested for 3.5 h after ingesting 0 (PLA), 2, or 6 (6CAF) mg·kg(-1) body mass of caffeine. The number of antigen-stimulated NK CD69(+) cells increased in 6CAF at 1 h compared with PLA (P = 0.021). Caffeine did not influence the number of antigen-stimulated CD69(+) T cells or the geometric mean fluorescence intensity expression of CD69 on antigen-stimulated lymphocytes, suggesting caffeine has little effect on antigen-stimulated lymphocyte activation.

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Citations

Mar 29, 2018·International Journal of Sport Nutrition and Exercise Metabolism·Ronald J MaughanLars Engebretsen
Mar 16, 2018·British Journal of Sports Medicine·Ronald J MaughanLars Engebretsen
Jun 3, 2021·International Journal of Molecular Sciences·Bianca S Romero-MartínezEdgar Flores-Soto

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