Effect of a nutritional liquid supplement designed for the patient with diabetes mellitus (Glucerna SR) on the postprandial glucose state, insulin secretion and insulin sensitivity in healthy subjects

Diabetes, Obesity & Metabolism
Manuel González-OrtizJosé A Robles-Cervantes

Abstract

To identify the effect of a nutritional liquid supplement designed for the patient with diabetes mellitus (Glucerna SR) in single administration on the postprandial glucose state, insulin secretion and insulin sensitivity in healthy subjects. A randomized, single-blind, cross-over, clinical trial was carried out in 14 young, healthy, non-obese, volunteers. A basal metabolic profile, which included glucose level, insulin, total cholesterol, high-density lipoprotein and low-density lipoprotein cholesterol, triglycerides, creatinine, and uric acid, was measured. Subjects received a single administration of 300 kcal, gauged with water at 350 ml, of each of the following (at least 3 days apart): glucose 75 g, polymeric supplement (Ensure high calcium) 315 ml or Glucerna SR 323 ml. At the beginning of each administration and 30, 60, 90 and 120 min later, glucose and insulin concentrations were measured. Areas under the curve of glucose and insulin were calculated. First-phase and total insulin secretions and insulin sensitivity were also estimated. Glucose level at 120 min was significantly lower after receiving Ensure high calcium or Glucerna SR. Administration of Glucerna SR resulted in a significant reduction in the areas under th...Continue Reading

References

Jan 1, 1992·JPEN. Journal of Parenteral and Enteral Nutrition·A L Peters, M B Davidson
Mar 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·W ScheppachH Kasper
Feb 1, 1988·Diabetes Care·A I Vinik, D J Jenkins
Jul 1, 1981·JPEN. Journal of Parenteral and Enteral Nutrition·S VanlandinghamS R Newmark
Apr 17, 1999·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·A M Coulston
Sep 26, 2001·Nutrition Reviews·R P LauberUNKNOWN American Heart Association
Dec 25, 2003·Diabetes Care·Marion J FranzUNKNOWN American Diabetes Association

❮ Previous
Next ❯

Citations

Feb 1, 2008·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Dimitrios PapandreouIoannis Mavromichalis
Nov 18, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·Manuel González-OrtizEsperanza Martínez-Abundis
Aug 3, 2011·Journal of Molecular Neuroscience : MN·Julie AngibaudHélène Boudin
Jan 16, 2014·Journal of Clinical Biochemistry and Nutrition·Saeko ImaiShizuo Kajiyama
Oct 18, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Related Papers

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
G RiccardiA A Rivellese
Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
H LochsC Pichard
© 2022 Meta ULC. All rights reserved