Effect of a pacing mode preserving spontaneous AV conduction on ventricular pacing burden and atrial arrhythmias

Pacing and Clinical Electrophysiology : PACE
Jean-Luc ReyMarc Hero

Abstract

Using dual-chamber pacemakers with new algorithms: Manage Ventricular Pacing (MVP™), minimizes unnecessary ventricular pacing (VP). This function operates in AAI/R mode with backup VP during AV block. The aim of "Generation MVP" study was to assess the VP burden and atrial arrhythmias (AA) burden according to indication of pacing and MVP™ function programming of AdaptaDR implantable pacemaker (Medtronic Inc., Minneapolis, MN, USA). The multicenter observational "Generation MVP" study included 220 patients aged 75.9 ± 11 years (men = 52%) implanted for sinus node dysfunction (SND; n = 115) or atrio-ventricular block (AVB; n = 105). Programming MVP function has been left to the physician's discretion. Percentage of VP and AA burden (percentage of time spent in AA) stored in memories were assessed at 2 and 10 months. 220 patients were followed at 2 months (174 MVP [On], 46 MVP [off]) and at 10 months (165 MVP [On], 55 MVP [off]). Median percentage of VP is significantly lower when MVP is programmed [On] versus [off] at 2 and 10 months follow-up for SND and AVB indications of pacing (P < 0.001). Finally, programming MVP function is performed at middle term (10 months) for 84% of patients with SND and 65% of patients with AVB: media...Continue Reading

References

Jun 14, 2002·The New England Journal of Medicine·Gervasio A LamasUNKNOWN Mode Selection Trial in Sinus-Node Dysfunction
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Michael O SweeneyTodd Sheldon
Aug 4, 2006·Pacing and Clinical Electrophysiology : PACE·Anne M GillisUNKNOWN Medtronic Enrhythm Clinical Study Investigators
Sep 7, 2007·The New England Journal of Medicine·Michael O SweeneyUNKNOWN Search AV Extension and Managed Ventricular Pacing for Promoting Atrioventricular Conduction (SAVE PACe) Trial
Feb 1, 2008·Pacing and Clinical Electrophysiology : PACE·Helmut PürerfellnerGoran Milasinovic
Jan 7, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Rick A VeaseyA Neil Sulke
Feb 9, 2011·European Heart Journal·Jens Cosedis NielsenUNKNOWN DANPACE Investigators

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Citations

Nov 27, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Bruce L WilkoffShu Zhang
Nov 21, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Bruce L WilkoffUNKNOWN Document Reviewers
Apr 27, 2021·Circulation·Emilio Arbas-RedondoCarlos A Álvarez-Ortega

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