Effect of a preoperative decontamination protocol on surgical site infections in patients undergoing elective orthopedic surgery with hardware implantation

JAMA Surgery
Serge P BebkoSamir S Awad

Abstract

Surgical site infections (SSIs), commonly caused by methicillin-resistant Staphylococcus aureus (MRSA), are associated with significant morbidity and mortality, specifically when hardware is implanted in the patient. Previously, we have demonstrated that a preoperative decontamination protocol using chlorhexidine gluconate washcloths and intranasal antiseptic ointment is effective in eradicating MRSA in the nose and on the skin of patients. To examine the effect of a decontamination protocol on SSIs in patients undergoing elective orthopedic surgery with hardware implantation. A prospective database of patients undergoing elective orthopedic surgery with hardware implantation at the Michael E. DeBakey Veterans Affairs Medical Center in Houston, Texas, was analyzed from October 1, 2012, to December 31, 2013. Cohort groups before and after the intervention were compared. Starting in May 2013, during their preoperative visit, all of the patients watched an educational video about MRSA decontamination and were given chlorhexidine washcloths and oral rinse and nasal povidone-iodine solution to be used the night before and the morning of scheduled surgery. Thirty-day SSI rates were collected according to the definitions of the Center...Continue Reading

Citations

Sep 22, 2016·Zeitschrift für Rheumatologie·J FussiL Renner
Mar 31, 2017·Orthopaedic Nursing·Mary Atkinson SmithMelissa Yager
Dec 12, 2017·The Journal of the American Academy of Orthopaedic Surgeons·Melvin Chugh MakhniK Daniel Riew
Aug 24, 2017·International Orthopaedics·Willem-Jan MetsemakersStefaan Nijs
May 19, 2017·The Cochrane Database of Systematic Reviews·Zhenmi LiuPeter Wilson
Sep 4, 2017·AORN Journal·Amber Wood
Jan 29, 2016·Clinical Microbiology Reviews·Edward J Septimus, Marin L Schweizer
Apr 24, 2019·Expert Review of Anti-infective Therapy·Adèle SakrOlivier Blin
Jun 25, 2016·Current Opinion in Clinical Nutrition and Metabolic Care·Monika A Krezalek, John C Alverdy
Sep 2, 2019·Current Infectious Disease Reports·Aurora Pop-Vicas, Nasia Safdar
Jul 2, 2019·The Journal of Craniofacial Surgery·Leila MusaviJordan P Steinberg
Jun 11, 2020·Ear, Nose, & Throat Journal·Samantha FrankBelachew Tessema
Feb 28, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Heather A LillemoeThomas A Aloia
Mar 13, 2019·Current Infectious Disease Reports·J Chase McNeil, Stephanie A Fritz
Nov 29, 2016·AORN Journal·Maureen Spencer
Aug 27, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Cindy MalletBrice Ilharreborde
Jan 8, 2018·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Daniel S UriasRussell Dumire
Mar 30, 2017·Neurosurgery·Paul A AndersonMohammed F Shamji
Jul 25, 2019·International Journal of Clinical Oncology·Mao NishikawaKanichi Seto
Dec 6, 2019·Journal of Family Medicine and Primary Care·Shekhar PalDeepak Juyal
Nov 17, 2020·Oral Diseases·Mao NishikawaKanichi Seto
Jan 15, 2021·The Spine Journal : Official Journal of the North American Spine Society·Bertrand DebonoHans D de Boer
Dec 12, 2020·Infectious Disease Clinics of North America·Sima L ShararaSara E Cosgrove
Jun 1, 2020·Annals of Vascular Surgery·Ahmed KhouqeerNeal R Barshes
Aug 14, 2021·Surgical Infections·Dominique M DockeryDioscaris R Garcia
Sep 18, 2021·Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews·Abdul Fettah BuyukChristopher Alcala
May 26, 2020·The Journal of Thoracic and Cardiovascular Surgery·Daniel T Engelman, Rakesh C Arora
Nov 20, 2021·Foot & Ankle International·Eitan M IngallChristopher W DiGiovanni

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