PMID: 59147Jul 10, 1976

Effect of a single dose of dexamethasone on serum concentrations of thyroid hormones

Lancet
W A BurrK W Wenzel

Abstract

In ten euthyroid subjects, in whom endogenous thyroid-stimulating hormone (T.S.H.) production was suppressed by oral thyroxine (T4), a single dose of dexamethasone resulted in reduced serum-3,3'5-triidothyronine (T3) concentration and raised serum-3,3',5'-triiodothyronine (reverse T3 or rT3) concentration after 24 h. These changes were not related to changes in free hormones or binding proteins. Adrenal glucocorticoids may have a pathophysiological role in modulating the peripheral metabolism of thyroid hormones in stress.

References

Mar 27, 1976·Lancet·A BurgerL E Braverman
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Apr 1, 1973·Clinical Endocrinology·R KirbyI D Johnston
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Citations

Jul 1, 1979·The American Journal of Cardiology·J C ForfarA D Toft
Sep 1, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·N BlomqvistJ Wålinder
Nov 1, 1976·Clinical Endocrinology·R S GriffithsR Hoffenberg
Apr 6, 2006·Journal of Veterinary Internal Medicine·Babetta A BreuhausSusan L Beyerlein
Apr 1, 1979·Journal of Clinical Pathology·R W PrescottD C Evered
Oct 1, 1992·Postgraduate Medical Journal·P BurraM C Sheppard
May 1, 1983·The Journal of Pediatrics·S R MoskowitzJ B Watkins
Dec 1, 1989·General and Comparative Endocrinology·R MeeuwisE R Kühn
Jan 15, 1998·The Journal of Pediatrics·C A StratakisG P Chrousos
Nov 14, 1997·The Journal of Clinical Endocrinology and Metabolism·M H Samuels, P A McDaniel
Apr 1, 1991·Journal of Endocrinological Investigation·U M Kabadi, L R Dragstedt
Jan 1, 1979·Acta Medica Scandinavica·G Kallner, J G Ljunggren
Sep 1, 1977·Scandinavian Journal of Clinical and Laboratory Investigation·K Liewendahl
Jan 1, 1980·Acta Medica Scandinavica·S Aanderud, H H Bassøe
Jul 1, 1988·The American Journal of Physiology·J T van der HeijdenR Docter
May 1, 1994·The American Journal of Physiology·M De JongG Hennemann
Mar 26, 2021·Journal of Endocrinological Investigation·G LiscoV Triggiani

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