Effect of a triclosan/copolymer dentifrice on the incidence of periodontal attachment loss in adolescents

Journal of Clinical Periodontology
R P EllwoodR M Davies

Abstract

The aim of this study was to assess the effectiveness of a dentifrice containing 0.3% triclosan, 2.0% copolymer and 0.243% sodium fluoride (Colgate Total) in the prevention of periodontal attachment loss in adolescents. A 3-year, double-blind, randomised, controlled, clinical trial was conducted on 641 adolescents, initially aged 11-13 years. The participants were enrolled from schools in economically deprived areas of Manchester, England, which had a high % of Asian pupils originating from India, Pakistan and Bangladesh. After the baseline examination, which included assessments of pocket depth, attachment loss and subgingival calculus, the adolescents were randomly allocated to use either a triclosan/copolymer or control dentifrice. The control was identical to the test dentifrice with the exception that it did not contain triclosan/copolymer. Participants were re-examined after 18 and 36 months. After 3 years, a total of 239 adolescents remained in the test and 241 in the control group. The prevalence of attachment loss increased from 2% at baseline to 24% after 3 years. The mean increment of attachment loss during the study was 0.025 mm per site in the control group and 0.018 mm per site in the test group. A linear regressi...Continue Reading

References

Sep 1, 1975·Community Dentistry and Oral Epidemiology·M A Lennon, R M Davies
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Citations

Aug 8, 2009·British Dental Journal·Anthony BlinkhornG J Seymour
Aug 9, 2003·British Dental Journal·R M DaviesR P Ellwood
Apr 25, 2001·The Journal of Prosthetic Dentistry·C A LefebvreG R Parr
Jan 12, 2005·Journal of Clinical Periodontology·M MustafaT Modéer
Aug 22, 2008·Periodontology 2000·Robin M Davies
Jun 28, 2005·Dental Clinics of North America·Andrew R DentinoErica J Renner
Dec 3, 2014·The Science of the Total Environment·Mary P CullinanGregory J Seymour
Sep 24, 2015·BMC Oral Health·Angelo Mariotti, Arthur F Hefti
Nov 6, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R M Davies
Aug 24, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R RautemaaG J Seymour
Jun 4, 2015·Brazilian Oral Research·Ernesto AndradeRui Vicente Oppermann
Oct 27, 2009·Brazilian Oral Research·Ricardo Palmier Teles, Flavia Rocha Fonseca Teles
Sep 2, 2005·Periodontology 2000·Martin Addy, Robert G Newcombe
Mar 13, 2002·Inquiry : a Journal of Medical Care Organization, Provision and Financing·K T CallT Rockwood
Jul 17, 2001·Periodontology 2000·V Clerehugh, A Tugnait
Jan 8, 2020·Clinical Oral Investigations·Mabelle Freitas MonteiroRenato Corrêa Viana Casarin

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