Effect of a xenograft on early bone formation in extraction sockets: an experimental study in dog

Clinical Oral Implants Research
M AraújoJ Lindhe

Abstract

The aim of this study was to study the effect on early bone formation resulting from the placement of a xenograft in the fresh extraction socket in dogs. Five beagle dogs were used. The distal roots of the third and fourth mandibular premolars were removed. In one quadrant, a graft consisting of Bio-Oss Collagen was placed in the fresh extraction wound, while the corresponding premolar sites in the contra-lateral jaw quadrant were left non-grafted. After 2 weeks of healing, the dogs were perfused with a fixative, the mandibles removed, the experimental sites dissected, demineralized, sectioned in the mesio-distal plane and stained in hematoxyline-eosine. The central portion of the non-grafted sockets was occupied by a provisional matrix comprised of densely packed connective tissue fibers and mesenchymal cells. Apical and lateral to the provisional matrix, newly formed woven bone was found to occupy most of the sockets. In the apical part of the grafted sockets, no particles of the xenograft could be observed but newly formed bone was present in this portion of the experimental site. In addition, limited numbers of woven bone trabeculae occurred along the lateral socket walls. The central and marginal segments of the grafted so...Continue Reading

References

Jan 1, 1967·The Journal of Prosthetic Dentistry·J Pietrokovski, M Massler
Jan 6, 2001·Journal of Clinical Periodontology·M G AraújoJ Lindhe
Feb 13, 2001·Clinical Oral Implants Research·M A MerkxH P Freihofer
Feb 13, 2001·International Journal of Experimental Pathology·A Vignery
Mar 27, 2003·Clinical Oral Implants Research·Daniela CarmagnolaTord Berglundh
Sep 6, 2003·Journal of Clinical Periodontology·G CardaropoliJ Lindhe
May 15, 2004·Clinical Oral Implants Research·Fabricio I TapetyTakeyasu Maeda
Feb 5, 2005·Journal of Clinical Periodontology·Mauricio G Araújo, Jan Lindhe
Mar 7, 2006·The International Journal of Periodontics & Restorative Dentistry·Myron NevinsBarry Wagenberg
Aug 8, 2006·Tissue Engineering·Daniël T LuttikhuizenMarja J A Van Luyn
Feb 20, 2007·Journal of Periodontal Research·B HoushmandB Eslami
Mar 17, 2007·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Jaime PietrokovskiIsrael Kaffe
Jul 20, 2007·Arthritis Research & Therapy·Brendan F Boyce, Lianping Xing

❮ Previous
Next ❯

Citations

Jul 21, 2012·Clinical Oral Investigations·Attila HorváthNikos Donos
Jun 28, 2012·International Journal of Dentistry·Giorgio PagniGiulio Rasperini
Jul 20, 2011·The Journal of Oral Implantology·Manuel NevesCélia Coutinho Alves
May 2, 2014·The Journal of Oral Implantology·Cleide Gisele RibeiroNeuza Maria Souza Picorelli Assis
Apr 14, 2015·Periodontology 2000·Mauricio G AraújoFlavia Sukekava
Mar 17, 2016·Annals of Maxillofacial Surgery·Daniela Guimaraes de MeloAna Cláudia Amorim Gomes Dourado
Mar 8, 2012·Acta Biomaterialia·Hanna TiainenHåvard J Haugen
Jan 7, 2016·Journal of Periodontal & Implant Science·Won-Sun BaekUi-Won Jung
Sep 25, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Alfonso CaiazzoPushkar Mehra
Jan 12, 2010·International Journal of Oral and Maxillofacial Surgery·S IibuchiS Echigo
Aug 27, 2014·Clinical Oral Implants Research·Minoru SandaShohei Kasugai
Aug 12, 2009·Clinical Oral Implants Research·Daniel S ThomaRonald E Jung
Sep 3, 2009·Journal of Clinical Periodontology·Stefan FicklMarkus B Hürzeler
Feb 9, 2012·Clinical Oral Implants Research·France LambertEric Rompen
Aug 18, 2010·Journal of Clinical Periodontology·Markus B HürzelerStefan Fickl
Nov 19, 2011·Clinical Oral Implants Research·Hsiang-Hsi HongChee-Jen Chang
Nov 26, 2010·Clinical Oral Implants Research·Mauricio G AraújoJan Lindhe
Nov 19, 2011·Clinical Oral Implants Research·Živko MladenovićMaria Ransjö
Jul 21, 2010·Journal of Clinical Periodontology·Daniel S ThomaChristoph H F Hämmerle
Jul 30, 2010·Clinical Oral Implants Research·Juan BlancoIsabel Ramos
Jan 26, 2013·Clinical Oral Implants Research·Mark Farmer, Ivan Darby
Mar 2, 2012·Clinical Implant Dentistry and Related Research·Pablo Galindo-MorenoFrancisco O'Valle
Jul 30, 2016·Progress in Biomaterials·Sergey V Dorozhkin
Jun 19, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jung-Seok LeeSeong-Ho Choi
Mar 11, 2015·Journal of Cellular and Molecular Medicine·Hsiang-Hsi HongTing-An Chou
Jul 22, 2014·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ji-Youn HongUi-Won Jung

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.