Effect of ac electric field on the dynamics of a vesicle under shear flow in the small deformation regime

Physical Review. E
Kumari Priti Sinha, R M Thaokar

Abstract

Vesicles or biological cells under simultaneous shear and electric field can be encountered in dielectrophoretic devices or designs used for continuous flow electrofusion or electroporation. In this work, the dynamics of a vesicle subjected to simultaneous shear and uniform alternating current (ac) electric field is investigated in the small deformation limit. The coupled equations for vesicle orientation and shape evolution are derived theoretically, and the resulting nonlinear equations are handled numerically to generate relevant phase diagrams that demonstrate the effect of electrical parameters on the different dynamical regimes such as tank treading (TT), vacillating breathing (VB) [called trembling (TR) in this work], and tumbling (TU). It is found that while the electric Mason number (Mn), which represents the relative strength of the electrical forces to the shear forces, promotes the TT regime, the response itself is found to be sensitive to the applied frequency as well as the conductivity ratio. While higher outer conductivity promotes orientation along the flow axis, orientation along the electric field is favored when the inner conductivity is higher. Similarly a switch of orientation from the direction of the ele...Continue Reading

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Citations

Aug 23, 2019·Soft Matter·Kumari Priti Sinha, Rochish M Thaokar
Apr 11, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Kumari Priti SinhaRochish M Thaokar

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