PMID: 6539134Apr 1, 1984Paper

Effect of acute alcoholic intoxication on the antigenic composition of soluble proteins in the rat brain

Biulleten' eksperimental'noĭ biologii i meditsiny
M S UsatenkoIu S Borodkin

Abstract

Cross immunoelectrophoresis was used to study antigenic composition of the brain of rats preferring water, or 15% ethanol and of intermediate group animals. The rat brain showed 6 antigens, one of them was found to be neurospecific. The intermediate group animals and those preferring ethanol differed from those preferring water in that they demonstrated two antigens which were found to be neuro-nonspecific. The content of the neurospecific protein S-100 in the cerebellum measured by rocket immunoelectrophoresis was demonstrated to be the same in animals preferring water and ethanol. A single intraperitoneal injection of 25% ethanol (2.5 g/kg) to the intermediate group rats brought about a change in the composition of neuro-nonspecific soluble antigens of the brain.

References

Sep 1, 1979·Journal of Neurochemistry·S P MahadikM M Rapport
Oct 2, 1979·Human Genetics·H W GoeddeD P Agarwal
Oct 16, 1978·Molecular Biology Reports·T G Bakayeva, V V Bakayev
Sep 1, 1975·Biulleten' eksperimental'noĭ biologii i meditsiny·P V SergeevV A Volov
Sep 1, 1988·Biulleten' eksperimental'noĭ biologii i meditsiny·S M Zimatkin, Iu M Ostrovskiĭ
Mar 1, 1967·Journal of Neurochemistry·E Kosinski, P Grabar
Jan 1, 1966·Biochemical Pharmacology·I A Sytinskii, T N Priyatkina
Nov 1, 1980·Biulleten' eksperimental'noĭ biologii i meditsiny·A I MaĭskiĭN K Borovkova
Feb 1, 1965·Analytical Biochemistry·C B LAURELL

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