PMID: 8938856Nov 1, 1996Paper

Effect of acute induced metabolic alkalosis on the acid/base responses to sprint exercise of six racing greyhounds

Research in Veterinary Science
S A HollowayD F Senior

Abstract

To investigate the effect of acute induced metabolic alkalosis on the haematological, biochemical and metabolic responses to sprint exercise, six greyhound dogs with previously placed carotid arterial catheters were raced four times over a distance of 400 metres. Each dog was raced twice after receiving oral sodium bicarbonate solution (NaHCO3) (400 mg kg-1) or lactated Ringer's solution (LRS). Before, and for intervals of up to one hour after, the exercise arterial blood samples were collected for the measurement of blood gases, packed cell volume, total protein, serum biochemistry and plasma lactate. The time to complete the 400 metre sprint ranged from 32.7 seconds to 36.9 seconds. There was no significant difference in racing times between the dogs treated with NaHCO3 and LRS, and there was no significant difference between the plasma lactate measurements after the treatments with NaHCO3 or LRS. Serum chloride concentrations were significantly lower after NaHCO3 than after LRS, and there was a trend towards a lower serum potassium concentration after NaHCO3 treatment. Plasma lactate concentrations showed a similar increase and time course of disappearance after both LRS and NaHCO3 treatments. There were significant changes ...Continue Reading

References

Mar 1, 1992·Equine Veterinary Journal·J D Harkins, S G Kamerling
Feb 1, 1986·Medicine and Science in Sports and Exercise·R J RobertsonJ R LeBoeuf

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Citations

Mar 14, 2018·Journal of Veterinary Emergency and Critical Care·Patricia G RosensteinDez Hughes
Mar 14, 2018·Journal of Veterinary Emergency and Critical Care·Patricia G RosensteinDez Hughes
Mar 27, 2018·Australian Veterinary Journal·S L KaramaticC S Mansfield
Feb 8, 1997·The Veterinary Record·A H Andrews, A Cox
Jun 19, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·L K VäihkönenA R Pösö
Feb 10, 2004·Journal of Applied Physiology·Graydon H RaymerR Terry Thompson

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