Effect of acute kidney injury on mortality and hospital stay in patient with severe acute pancreatitis

Nephrology
Jiaojiao ZhouPing Fu

Abstract

Severe acute pancreatitis (SAP) is believed to be a major risk factor leading to acute kidney injury (AKI) among critically ill patients, but little is known about SAP-induced AKI. We study the incidence of AKI defined by the Acute Kidney Injury Network (AKIN) criteria and the risk factors associated with outcomes among SAP-induced AKI patients. We conducted a multicenter retrospective study of critically ill SAP-induced AKI patients during the period August 2009 to June 2013. Data on enrolled patients were retrieved from electronic records. Univariate and multiple regression analyses were performed. Among a total of 414 SAP patients admitted to intensive care units(ICU), 287 (69.3%) developed AKI during their ICU stay, with 16.7%, 18.4%, and 34.3% classified as AKI stage I,II, and III, respectively. SAP-induced AKI patients experienced a significantly higher ICU mortality than those without AKI. The risk factors associated with ICU mortality among SAP-induced AKI patients included ACS (odds ratio (OR) 10.58), RRT (OR 3.31), sepsis (OR 2.46), CTSI (OR 3.01), APACHE II score (OR 1.82), AKI III (OR 1.38), ICU-length-of-stay (OR 1.04), and multi-organ failure. The paper represents the first attempt to investigate the etiology and ...Continue Reading

References

Jun 1, 1992·Critical Care Medicine·R C BoneW J Sibbald
Feb 1, 1990·Radiology·E J BalthazarJ H Ranson
Oct 1, 1987·Critical Care Medicine·R W ChangB Lee
Dec 1, 1985·Annals of Surgery·W A KnausJ E Zimmerman
Jul 1, 1996·Renal Failure·P KesA Fotivec
Jul 1, 1996·Renal Failure·D LjutićP Andrews
Apr 19, 2002·Journal of the American Society of Nephrology : JASN·Ravindra L MehtaGlenn M Chertow
Mar 28, 2003·Journal of the American Society of Nephrology : JASN·Eric A J HosteFrancis A Colardyn
May 16, 2003·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·L CompañyM Pérez-Mateo
Sep 29, 2004·European Journal of Internal Medicine·Alexander Wilmer
Oct 27, 2004·AJR. American Journal of Roentgenology·Koenraad J MorteleStuart G Silverman
Aug 18, 2005·JAMA : the Journal of the American Medical Association·Shigehiko UchinoUNKNOWN Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators
Sep 24, 2005·Journal of the American Society of Nephrology : JASN·Glenn M ChertowDavid W Bates
Aug 19, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Sean M BagshawUNKNOWN Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators
Mar 4, 2008·The International Journal of Artificial Organs·E A HosteC Ronco
Jun 28, 2008·Langenbeck's Archives of Surgery·Jean-Louis Vincent
Aug 30, 2008·Critical Care : the Official Journal of the Critical Care Forum·José António LopesMateus Martins Prata
Mar 25, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Z Birsin OzçakarMesiha Ekim
Dec 28, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jan J De WaeleEric Hoste
Jan 22, 2011·Upsala Journal of Medical Sciences·Hung-Yuan LinGau-Jun Tang
May 14, 2011·Journal of the American Society of Nephrology : JASN·Abolfazl Zarjou, Anupam Agarwal
May 24, 2012·Lancet·Rinaldo BellomoClaudio Ronco
Jul 13, 2012·Clinical Medicine : Journal of the Royal College of Physicians of London·Mike Jones
Feb 12, 2013·Critical Care : the Official Journal of the Critical Care Forum·John A KellumUNKNOWN KDIGO AKI Guideline Work Group
May 11, 2013·Critical Care Research and Practice·Polychronis PavlidisMarlies Ostermann
Jun 19, 2013·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Nadezda Petejova, Arnost Martinek
Oct 8, 2013·Critical Care : the Official Journal of the Critical Care Forum·Matthieu LegrandJean-Luc Mainardi

❮ Previous
Next ❯

Citations

Mar 30, 2016·Mediators of Inflammation·Mateusz SporekBeata Kusnierz-Cabala
Apr 2, 2019·Journal of Zhejiang University. Science. B·Wen-Qiao YuTing-Bo Liang
Sep 19, 2019·Revista da Associação Médica Brasileira·Reginaldo Passoni Dos SantosEtienne Macedo
May 24, 2019·Clinical Journal of the American Society of Nephrology : CJASN·Tareq I Nassar, Wajeh Y Qunibi
Aug 26, 2017·World Journal of Gastroenterology : WJG·Amir GougolGeorgios I Papachristou
Aug 2, 2019·International Journal of Molecular Sciences·Justyna WajdaBeata Kuśnierz-Cabala
Mar 29, 2020·Digestive Diseases and Sciences·Deliang MaDianliang Zhang
Mar 16, 2019·Veterinary Sciences·Eleonora GoriVeronica Marchetti
Feb 26, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Xiao-Lin YiWen-Fu Tang
May 25, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Aravind ThavamaniSenthilkumar Sankararaman
May 27, 2021·Journal, Genetic Engineering & Biotechnology·Ombretta ParaCarlo Nozzoli
Jul 5, 2021·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Xihong ZhangWeiqin Li

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.