Effect of adding oat bran to instant oatmeal on glycaemic response in humans - a study to establish the minimum effective dose of oat β-glucan

Food & Function
Thomas M S WoleverRobert E Steinert

Abstract

Reducing the glycaemic response to carbohydrate-containing foods may have desirable physiological effects for many people. Here, we aimed to determine the minimum amount of oat β-glucan from oat-bran which, when added to instant-oatmeal, would reduce the glycaemic response by 20% compared to a β-glucan-free cereal. Therefore, the glycaemic responses elicited by one serving (27 g) instant-oatmeal plus 247 g 2% milk (IO, 28 g available-carbohydrate, 1.2 g β-glucan) or IO plus 0.2, 0.4, 0.8 or 1.6 g oat β-glucan (OBG) from oat-bran, or an available-carbohydrate matched portion of cream of rice (CR) plus milk were measured over 2 h in n = 40 subjects using a randomized, cross-over design. The primary endpoint was incremental area under the curve (iAUC). The secondary endpoint was glucose peak-rise. The results showed that grams OBG consumed were significantly correlated with mean iAUC (p = 0.009) and with mean glucose peak-rise (p = 0.002). Each gram of OBG reduced iAUC by 7% and peak-rise by 15%. Thus, to achieve a ≥20% reduction in iAUC relative to CR, 1.6 g OBG had to be added to IO (74 ± 7 vs. 93 ± 6 mmol min L-1, p < 0.05), but, to achieve a 20% reduction in peak-rise, only 0.4 g OBG was required (2.00 ± 0.1 vs. 2.40 ± 0.1 mmo...Continue Reading

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Citations

Dec 6, 2019·Journal of the Science of Food and Agriculture·Emely Osti ZanonRafael Fagnani
Sep 11, 2019·Nutrition and Health·Maximilian Andreas Storz, Onno Küster
Jun 4, 2020·Revista brasileira de enfermagem·Elen Cristiane Doná OliveiraSilvia Justina Papini
Sep 25, 2020·Diabetes Research and Clinical Practice·Rukiye BozbulutPeyami Cinaz
Dec 29, 2020·Critical Reviews in Food Science and Nutrition·Marcus Schmidt
Feb 21, 2021·European Journal of Clinical Nutrition·Andreea ZurbauThomas M S Wolever
Aug 28, 2021·Nutrients·Sylwia GudejJoanna Gromadzka-Ostrowska

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Clinical Trials Mentioned

NCT02818452

Software Mentioned

excel
GraphPad
GraphPad Prism

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