Effect of aerobic and resistance exercise training on inflammation, endothelial function and ambulatory blood pressure in middle-aged hypertensive patients.

Journal of Hypertension
Francesco P BoenoAlvaro Reischak-Oliveira

Abstract

The current randomized controlled trial tested the hypothesis that both aerobic training and dynamic resistance training will improve inflammation, endothelial function and 24-h ambulatory blood pressure (ABP) in middle-aged adults with hypertension, but aerobic training would be more effective. Forty-two hypertensive patients on at least one antihypertensive medication (19 men/23 women; 30-59 years of age) were randomly assigned to 12 weeks of supervised aerobic training (n = 15), resistance training (n = 15) or a nonexercise control (n = 12) group. Inflammation, endothelial function, 24-h ABP and related measures were evaluated at pre and postintervention. We found that aerobic training and resistance training were well tolerated. Both aerobic training and resistance training reduced daytime systolic ABP (-7.2 ± 7.9 and -4.4 ± 5.8 mmHg; P < 0.05) and 24-h systolic ABP (-5.6 ± 6.2 and -3.2 ± 6.4 mmHg; P < 0.05). aerobic training and resistance training both improved brachial artery flow-mediated dilation by 1.7 ± 2.8 and 1.4 ± 2.6%, respectively (7.59 ± 3.36 vs. 9.26 ± 2.93 and 7.24 ± 3.18 vs. 8.58 ± 2.37; pre vs. post P < 0.05). However, only aerobic training decreased markers of inflammation (C-reactive protein, monocyte che...Continue Reading

References

Jan 1, 1994·Annual Review of Medicine·M P BevilacquaO Cecconi
Dec 1, 1998·The American Journal of Cardiology·W C LevyJ R Stratton
Jun 21, 2001·Biochemical and Biophysical Research Communications·H MorawietzJ Holtz
Apr 13, 2004·Medicine and Science in Sports and Exercise·Linda S PescatelloUNKNOWN American College of Sports Medicine
Sep 28, 2006·Nature Clinical Practice. Nephrology·Nosratola D Vaziri, Bernardo Rodríguez-Iturbe
Jan 6, 2010·Hypertension·Toni M TinkenDaniel J Green
Mar 27, 2010·The International Journal of Cardiovascular Imaging·Yoichi InabaSteven R Bergmann
Apr 3, 2010·Clinics·Crivaldo Gomes CardosoClaudia Lucia de Moraes Forjaz
Jul 18, 2012·Hypertension·Fernando DimeoTimm H Westhoff
Jan 18, 2013·Journal of Hypertension·Véronique A CornelissenNeil A Smart
Sep 3, 2013·Physiology·Carmen Fiuza-LucesAlejandro Lucia
Nov 30, 2014·Current Hypertension Reports·Carmen De MiguelDavid L Mattson
Aug 19, 2015·Sports Medicine - Open·Juliano Boufleur FarinhaFélix Alexandre Antunes Soares
Aug 16, 2016·Journal of Applied Physiology·Crystal L CoolbaughTheodore F Towse
Aug 5, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Evitom Corrêa de SousaRodolfo Paula Vieira
Aug 25, 2018·Journal of the American College of Cardiology·Johan S R ClausenMagnus T Jensen
Nov 6, 2018·Experimental Gerontology·Josianne Rodrigues-KrauseAlvaro Reischak-Oliveira
Nov 30, 2018·Journal of the American Society of Hypertension : JASH·Marinei L PedralliAlexandre Machado Lehnen
Jun 19, 2019·European Heart Journal·Dick H J ThijssenLorenzo Ghiadoni

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Citations

Dec 23, 2020·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Francesco P BoenoAlvaro Reischak-Oliveira
Mar 10, 2021·BMC Sports Science, Medicine and Rehabilitation·Jamal Shaker OmarAbdel Naser Qadoumi
May 20, 2021·Arquivos brasileiros de cardiologia·Gustavo F OliveiraLeandro C Brito
Jun 22, 2021·Current Hypertension Reports·Rafael Y FecchioCláudia Lúcia de Moraes Forjaz
Jul 30, 2021·Journal of Human Hypertension·Odilon AbrahinJoão Farias Guerreiro
Aug 18, 2021·Atherosclerosis·Jessika Karla T N F SilvaBreno Q Farah

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