Effect of aerobic exercise training on renal responses to sodium in hypertensives

Medicine and Science in Sports and Exercise
Donald R DengelMark A Supiano

Abstract

Aerobic exercise training has been shown to improve cardiovascular function and lower blood pressure (BP) in older adults. The exact mechanism(s) by which aerobic exercise training elicits these changes are unknown; however, it is possible that changes in renal hemodynamics may play a role. The present study was undertaken to examine the effect of aerobic exercise training on renal hemodynamics in older hypertensive individuals. Renal plasma flow (RPF) and glomerular filtration rate (GFR) were determined by plasma and urinary clearances of 131I-hippuran and 99mTc-DTPA after 8 d of low (20 mEq) and high (200 mEq) Na+ diets in 31 older (63 +/- 1 yr), hypertensive (152 +/- 2/88 +/- 1 mm Hg) individuals at baseline and following 6 months of aerobic exercise training (at 75% VO2max, three times a week, 40 min per session). Following 6 months of aerobic exercise training, a significant increase was seen in maximal aerobic capacity (VO2max: 18.3 +/- 0.7 vs 20.7 +/- 0.7 mL.kg.min(-1), P = 0.017) as well as a significant decrease in resting systolic (152 +/- 2 vs 145 +/- 2 mm Hg, P = 0.037) and mean arterial (109 +/- 1 vs 105 +/- 1 mm Hg, P = 0.021) BP. No significant (P < 0.05) effects were seen of aerobic exercise training on RPF (208...Continue Reading

References

Jul 1, 1992·Journal of the American Society of Nephrology : JASN·D K KlassenE U Buddemeyer
Aug 1, 1991·Circulation Research·G KimuraM Kawamura
Nov 1, 1991·The Journal of Clinical Endocrinology and Metabolism·T J McKennaS Cunningham
Aug 1, 1989·The American Journal of Cardiology·J M HagbergA A Ehsani
Sep 1, 1995·Medicine·L H RileyL H Riley
Dec 1, 1994·Sports Medicine·J R Poortmans, J Vanderstraeten
Aug 1, 1997·American Journal of Hypertension·K KohnoT Imaizumi
Oct 16, 1999·Journal of the American College of Cardiology·R W BraithC J Pepine
Sep 22, 2000·Sports Medicine·J M HagbergM D Brown
Mar 8, 2003·Scandinavian Journal of Urology and Nephrology·E SvarstadB M Iversen

❮ Previous
Next ❯

Citations

Nov 17, 2009·American Journal of Physiology. Heart and Circulatory Physiology·Chester A Ray, Jason R Carter
Dec 2, 2010·Journal of Hypertension·Nora E StraznickyMarkus P Schlaich

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Forensic Sciences
Tina K KastowskyJohan A Duflou
Medicine and Science in Sports and Exercise
Kerri M Winters-Stone, Christine M Snow
Journal of Pediatric Endocrinology & Metabolism : JPEM
Małgorzata MyśliwiecAndrzej Myśliwski
© 2021 Meta ULC. All rights reserved