Effect of age and disease on bone mass in Japanese patients with schizophrenia.

Annals of General Psychiatry
Norio SugawaraSunao Kaneko

Abstract

There have been a limited number of studies comparing bone mass between patients with schizophrenia and the general population. The aim of this study was to compare the bone mass of schizophrenia patients with that of healthy subjects in Japan. We recruited patients (n = 362), aged 48.8 ± 15.4 (mean ± SD) years who were diagnosed with schizophrenia or schizoaffective disorder based on the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV). Bone mass was measured using quantitative ultrasound densitometry of the calcaneus. The osteosono-assessment index (OSI) was calculated as a function of the speed of sound and the transmission index. For comparative analysis, OSI data from 832 adults who participated in the Iwaki Health Promotion Project 2009 was used as representative of the general community. Mean OSI values among male schizophrenic patients were lower than those in the general population in the case of individuals aged 40 and older. In females, mean OSI values among schizophrenic patients were lower than those in the general community in those aged 60 and older. In an analysis using the general linear model, a significant interaction was observed between subject groups and age in males. Older sc...Continue Reading

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Nov 23, 2011·Human Psychopharmacology·Norio SugawaraSunao Kaneko

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Citations

Jul 22, 2014·Acta Psychiatrica Scandinavica·B StubbsD Vancampfort
Aug 5, 2016·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Chien-Yu ChenChieh-Hsin Lin
Jun 30, 2012·Current Opinion in Psychiatry·Taishiro KishimotoChristoph U Correll

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