Effect of age and disease on taste perception

Journal of Pain and Symptom Management
Kenway NgC J K Henry

Abstract

Abnormalities in taste function may contribute to poor dietary intake in the elderly, and in patients with renal failure or cancer. This study examined the effect of age on taste thresholds, and taste thresholds adjusted for age, in patients with renal failure with and without dialysis, and patients with cancer receiving chemotherapy and/or radiotherapy. Three groups of healthy volunteers aged 21-34 (n=26), 36-61 (n=13), and 69-94 (n=24), were recruited for the study on the effect of age. Nineteen patients with chronic renal failure on chronic ambulatory peritoneal dialysis (CAPD) and 11 age-matched chronic renal failure patients not yet requiring dialysis were recruited to examine the effect of chronic renal failure on taste function. Twenty-four inpatients with various types of cancer were recruited from a clinical oncology ward. Taste threshold was measured using commercial flavors supplied by Firmenich (pork, beef) and the ascending forced-choice method. Results showed that taste threshold increased with age. No abnormality in taste threshold was observed in patients with chronic renal failure with and without dialysis, and in patients with cancer. However, altered taste occurred in a large number of these patients. Abnorma...Continue Reading

References

Jan 1, 1978·The American Journal of Clinical Nutrition·L R Williams, M H Cohen
Jul 1, 1978·International Journal of Radiation Oncology, Biology, Physics·K L Mossman, R I Henkin
Jul 15, 1983·Cancer·S KamathW P McGuire
Dec 1, 1982·The American Journal of Clinical Nutrition·S K MahajanF D McDonald
Jan 1, 1980·Nephron·M CiechanoverJ E Steiner
May 1, 1995·Journal of the American Geriatrics Society·D H SullivanM M Bopp
Jan 1, 1993·Critical Reviews in Food Science and Nutrition·J C Stevens, W S Cain
Jul 1, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A M MaddenM Y Morgan
Aug 24, 2001·Journal of the American Society of Nephrology : JASN·Angela Yee Moon WangJohn Elsby Sanderson
Aug 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Cheryl L Rock, Wendy Demark-Wahnefried
May 2, 2003·Age and Ageing·Marcel G M Olde Rikkert, Anne-Sophie Rigaud
Jul 10, 2003·International Journal of Food Sciences and Nutrition·C Jeya K HenryTeodros A Seyoum

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Citations

Jul 30, 2010·The Oncologist·August ZaberniggBernhard Holzner
Nov 22, 2012·Oral Oncology·Canhua XiaoDeborah Watkins Bruner
Oct 11, 2012·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Katherine E LynchSteven M Brunelli
May 27, 2011·Cancer Treatment Reviews·Anna Boltong, Russell Keast
Jan 18, 2011·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Maurizio BossolaLuigi Tazza
Apr 22, 2015·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·H KellerH Payette
Aug 5, 2006·Cancer Treatment Reviews·Maria Grazia Ruo Redda, Simona Allis
Mar 25, 2015·Chemical Senses·Giuseppe RivaMassimiliano Garzaro
Oct 29, 2005·European Journal of Clinical Nutrition·B J Stewart-KnoxJ J Strain
Jan 11, 2019·Chemical Senses·Ciara FitzgeraldCordelia A Running
Jan 26, 2006·European Journal of Clinical Nutrition·U SimchenH-J F Zunft
Feb 29, 2008·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Heather H KellerH Gayle Edward
Feb 6, 2017·PloS One·Jose Carlos Fernandez-GarciaLourdes Garrido-Sanchez
May 17, 2017·Obesity Surgery·Carlos ZerrweckLizbeth Guilber
Oct 9, 2020·Pflügers Archiv : European journal of physiology·Elena von MolitorTiziana Cesetti
Jul 10, 2021·Frontiers in Human Neuroscience·Elena von MolitorTiziana Cesetti
Jul 6, 2021·Clinical and Experimental Nephrology·Yuko OhtaYuhei Kawano

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