Effect of age and preexisting antibody on serum antibody response of infants and children to the F and G glycoproteins during respiratory syncytial virus infection.

Journal of Clinical Microbiology
B R MurphyB S Graham

Abstract

The serum antibody response of 50 infants and children infected with respiratory syncytial virus (RSV) was determined by a glycoprotein-specific enzyme-linked immunosorbent assay, and the effects of age and preexisting antibody titer at the time of RSV infection on response to the G and F glycoproteins of RSV were examined. The immune response to the G and F glycoproteins was assessed with anti-human immunoglobulin A to permit measurement of the response of young infants in the presence of maternally derived immunoglobulin G. The findings suggested that age primarily affects the response to the F glycoprotein and that preexisting antibody titer affects the response to the G glycoprotein.

References

Jul 1, 1978·The Journal of Infectious Diseases·K McIntoshR M Barkin
Apr 1, 1985·The Journal of Infectious Diseases·L J AndersonK McIntosh
Apr 1, 1985·The Journal of Infectious Diseases·G A PrinceR M Chanock
Mar 1, 1985·The Journal of General Virology·E E WalshJ J Schlesinger
Mar 1, 1985·The Journal of General Virology·C Gruber, S Levine

❮ Previous
Next ❯

Citations

Mar 3, 1999·Proceedings of the National Academy of Sciences of the United States of America·A BukreyevP L Collins
Sep 21, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·J E CroweB R Murphy
Jan 20, 2004·The Pediatric Infectious Disease Journal·Fernando P Polack, Ruth A Karron
Jan 1, 2006·Expert Review of Clinical Immunology·Weidong ZhangShyam S Mohapatra
Apr 12, 2013·Clinical Reviews in Allergy & Immunology·Andrea T BorchersLaurel J Gershwin
Oct 18, 2014·Frontiers in Immunology·Laura LambertFiona J Culley
Sep 1, 1992·European Journal of Pediatrics·M L Everard, A D Milner
Aug 1, 1996·The Pediatric Infectious Disease Journal·R A KarronB R Murphy
Aug 2, 2002·The Pediatric Infectious Disease Journal·Pedro A Piedra
Aug 16, 2008·The Journal of Infectious Diseases·Joshua J ShinoffRuth A Karron
Mar 20, 2013·Proceedings of the National Academy of Sciences of the United States of America·John S TregoningPeter J Openshaw
Oct 13, 2015·Expert Opinion on Investigational Drugs·Claudia A RiveraAlexis M Kalergis
Feb 24, 2016·Human Vaccines & Immunotherapeutics·Susanna EspositoNicola Principi
May 29, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Andrea G BuchwaldMilagritos D Tapia
Oct 1, 1991·FEMS Microbiology Immunology·G L Toms
Feb 1, 1997·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·O StrannegårdN Sigurs
Jan 1, 1990·Archives of Virology·T G Kimman, F Westenbrink
Oct 12, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J E Crowe
Oct 22, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jörn-Hendrik WeitkampJames E Crowe
Sep 28, 2006·Reviews in Medical Virology·S van Drunen Littel-van den HurkJ Kovacs-Nolan
Apr 3, 2003·The Pediatric Infectious Disease Journal·Pedro A Piedra
Sep 24, 2013·Expert Review of Vaccines·Vanessa KurzweilMark T Esser
Nov 15, 2013·Reviews in Medical Virology·Jop JansGerben Ferwerda
Mar 1, 1996·Archives of Disease in Childhood·I M Balfour-Lynn

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.