Effect of age on oral contraceptive-induced venous thrombosis

Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
A GirolamiG Luzzatto

Abstract

This study was undertaken to investigate the effect of age on oral contraceptive-induced venous thrombosis. All women seen in the University of Padua Department of Medical and Surgical Science who had had two courses of oral contraceptive therapy at different ages were included. A total of 28 subjects met these criteria. Fifteen patients had a congenital or acquired prothrombotic condition, whereas 13 women were normal subjects. The mean age at which thrombosis occurred was 33.3 and 36.3 years for women with or without a prothrombotic condition, respectively. The ages during which the women remained asymptomatic were 23.1 and 23.3 years for women with or without a predisposing defect, respectively. Thrombosis occurred, during the second course of oral contraceptive therapy, after the mean duration of 6.5 cycles or 18.4 cycles in women with or without prothrombotic defects, respectively. During the asymptomatic course, approximately the same number of women took old progestins or third-generation compounds. On the contrary, during the second period, 21 of 28 women took progestins with third-generation compounds. Age seems to plays an important role in oral contraceptive-induced venous thrombosis. In normal women, thrombosis occu...Continue Reading

References

Aug 1, 1992·Journal of Internal Medicine·M NordströmT Kjellström
Feb 1, 1992·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·A GirolamiS Zanardi
Oct 1, 1991·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·A GirolamiS Zanardi
May 1, 1968·The British Journal of Surgery·M T Morrell, M S Dunnill
Apr 25, 1994·Archives of Internal Medicine·W D KniffinF A Anderson
Jan 24, 1994·Archives of Internal Medicine·A CogoA Girolami
Sep 1, 1996·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·A GirolamiP Radossi
Feb 12, 1998·Annals of Internal Medicine·D T Price, P M Ridker
Jul 23, 1998·Contraception·O LidegaardS Kreiner
Feb 13, 1999·American Journal of Obstetrics and Gynecology·G Weiss
Feb 1, 2000·Human Reproduction Update·J Conard
Feb 1, 2000·Human Reproduction Update·W O Spitzer
Jul 21, 2000·BMJ : British Medical Journal·D C Skegg
May 18, 2001·The New England Journal of Medicine·J P VandenbrouckeF R Rosendaal
Jun 19, 2003·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Antonio GirolamiFabrizio Fabris

❮ Previous
Next ❯

Citations

Feb 1, 2007·Journal of Thrombosis and Thrombolysis·Antonio GirolamiBruno Girolami
Sep 17, 2011·Contraception·Johannes Bitzer, James A Simon
Nov 5, 2016·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org, UNKNOWN Practice Committee of the American Society for Reproductive Medicine
Oct 26, 2005·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Antonio GirolamiFabrizio Fabris
Jun 16, 2016·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·A GirolamiB Girolami
Mar 5, 2014·The Cochrane Database of Systematic Reviews·Marcos de BastosOlaf M Dekkers
Nov 12, 2010·The Journal of Family Planning and Reproductive Health Care·Anne SzarewskiLee P Shulman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.