Effect of age on the pupillomotor field

Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
Ruediger SchmidHelmut Wilhelm

Abstract

To differentiate physiologic variation from visual field loss with pupillomotor perimetry, the effect of age on the normal pupillomotor field must be known. Given the absence of reported data, the authors aimed to analyze the effect of age on the pupillomotor field as measured with light stimuli of different properties. Subjects consisted of 23 healthy volunteers aged 20 to 28 years ("younger subjects") and 20 healthy volunteers aged 50 to 67 years ("older subjects"). Within a field of 20 degrees, a sequence of 25 focal light stimuli was performed repeatedly on a monitor. The pupil light reflex (PLR) was recorded to stimuli of different diameter and luminance under mesopic conditions. The mean amplitude of the PLR was calculated for each stimulus location and condition. Increasing stimulus luminance or size caused a larger PLR amplitude and a steeper decline of the PLR amplitude from the center to the periphery of the pupillomotor field. The older subjects had reduced mean PLR amplitude with a less pronounced decrease of PLR amplitude toward the field periphery. For the peripheral locations, the largest PLR amplitude was found in the temporal superior quadrants. There was considerable intra-individual test-retest variation in P...Continue Reading

References

Jan 1, 1979·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·K U HamannS Zschocke
Dec 1, 1975·Archives of Ophthalmology·G W CibisE Aulhorn
Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·J B JonasG O Naumann
Nov 1, 1992·Archives of Ophthalmology·D G Birch, J L Anderson
Oct 1, 1990·The Journal of Comparative Neurology·C A Curcio, K A Allen
Feb 22, 1990·The Journal of Comparative Neurology·C A CurcioA E Hendrickson
Jan 1, 1988·Vision Research·M Fahle, M Schmid
Jan 1, 1987·Documenta Ophthalmologica. Advances in Ophthalmology·L R Trick
Jan 1, 1986·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·R S Brenton, C D Phelps
Jan 1, 1986·Archives of Ophthalmology·J Katz, A Sommer
Feb 15, 1986·American Journal of Ophthalmology·A HaasU Schneider
Jan 1, 1971·American Journal of Ophthalmology·I E Loewenfeld, D A Newsome
Jun 1, 1984·American Journal of Ophthalmology·A G BalazsiG R Douglas
Sep 1, 1994·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M Zulauf
Mar 1, 1993·Annals of Neurology·C A Curcio, D N Drucker
Aug 6, 1998·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·M L HennellyE G Woodward
Sep 5, 1992·Current Opinion in Ophthalmology·R H Kardon

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Citations

Jul 30, 2010·Clinical Ophthalmology·Ken AsakawaKimiya Shimizu
Dec 18, 2010·Neurología : publicación oficial de la Sociedad Española de Neurología·F Martínez-RicarteJ Aparicio
Jul 23, 2021·Eye·Hilal Kılınç HekimsoyPelin Yılmazbaş

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