PMID: 8460698Mar 1, 1993Paper

Effect of aging and bolus variables on pharyngeal and upper esophageal sphincter motor function

The American Journal of Physiology
R ShakerJ Hintz

Abstract

Effect of aging, bolus volume, temperature, and consistency on the pharyngeal peristalsis, as well as the effect of aging on the upper esophageal sphincter (UES) resting pressure and its response to esophageal distension by air and balloon, were studied in 14 young and 12 healthy elderly volunteers. In both age groups there was no significant volume or temperature effect on amplitude, duration, or velocity of the pharyngeal peristalsis. Compared with water swallows, mashed potato swallows resulted in a significant increase in the amplitude and duration of the hypopharyngeal peristaltic pressure wave (P < 0.05). For water swallows, the amplitude and duration of the peristaltic pressure wave in the hypopharynx were significantly increased in the elderly compared with the young group (P < 0.01). UES resting pressure in the elderly measured 43 +/- 5 (SE) mmHg and was significantly less than that of the young (71 +/- 8 mmHg; P < 0.01). Magnitude of the UES pressure decrease because of esophageal distension by air, as well as magnitude of its pressure increase because of esophageal balloon distension, was similar among young and elderly. 1) Contrary to common expectations, the parameters of the pharyngeal peristaltic pressure wave do...Continue Reading

Citations

Nov 16, 2002·American Journal of Physiology. Gastrointestinal and Liver Physiology·William C Orr, C L Chen
Jul 19, 2013·Dysphagia·Christina H SmithSarah Simpson
Oct 1, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Luciana C SilvaMarco G Patti
Aug 1, 2000·American Journal of Physiology. Gastrointestinal and Liver Physiology·S TorricoR Shaker
Jan 17, 2003·American Journal of Physiology. Gastrointestinal and Liver Physiology·Bidyut K MeddaReza Shaker
Apr 29, 2006·American Journal of Physiology. Gastrointestinal and Liver Physiology·Sudip K GhoshPeter J Kahrilas
Mar 4, 2017·American Journal of Physiology. Gastrointestinal and Liver Physiology·Mark K KernReza Shaker
Feb 14, 2006·American Journal of Physiology. Gastrointestinal and Liver Physiology·Eytan BardanReza Shaker
Dec 19, 2002·American Journal of Physiology. Gastrointestinal and Liver Physiology·Khalil N Bitar
Nov 10, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Julia GatesGary D Gramigna
May 17, 2006·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E BardanR Shaker
May 21, 2016·American Journal of Physiology. Gastrointestinal and Liver Physiology·Hongmei JiaoReza Shaker
Mar 16, 2000·The American Journal of Medicine·R Shaker, W J Hogan

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