Effect of aging on optical quality and intraocular scattering using the double-pass instrument

Current Eye Research
Kazutaka KamiyaHiroshi Uozato

Abstract

To assess the effect of aging on optical quality in a normal population. We prospectively examined 100 normal eyes of 100 healthy volunteers (50 men, 50 women; ages, 20-69 years; mean age ± standard deviation, 44.6 ± 15.5 years). We quantitatively assessed the values of MTF cutoff frequency, Strehl ratio, and objective scattering index (OSI), using an Optical Quality Analysis System™ (Visiometrics, Terrassa, Spain). We took these measurements three times each, and the mean value obtained was used for statistical analysis. We investigated the relationships between subject age and these optical quality parameters. The mean MTF cutoff frequency, Strehl ratio, and OSI, were 27.76 ± 8.41, 0.17 ± 0.05, and 1.29 ± 0.76 cycles/degree, respectively. We found a significant negative correlation between subject age and MTF cutoff frequency (Pearson's correlation coefficient r = -0.606, p < 0.001), and between age and Strehl ratio (r = -0.649, p < 0.001). We also found a significant positive correlation between subject age and OSI (r = 0.691, p < 0.001). The MTF cutoff frequency and the Strehl ratio are significantly decreased, and the OSI is significantly increased, by aging, indicating that the optical quality of the eye is degraded in ol...Continue Reading

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Citations

Apr 23, 2014·Current Eye Research·Clemente Paz FilgueiraLuis A Issolio
Aug 3, 2013·Korean Journal of Ophthalmology : KJO·Hyeong-Gi Jung, Tae-Hyung Lim
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Sep 5, 2018·BMC Ophthalmology·Jin Sun HwangYoung Joo Shin
Nov 10, 2018·Journal of Ophthalmology·Hao-Chen GuoA-Yong Yu
Jun 29, 2017·Journal of Ophthalmology·Jing GaoQi Zhao
May 6, 2021·International Journal of General Medicine·Xiaoyan BianJun Liu

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