PMID: 2491802Jan 1, 1989Paper

Effect of altering heart rate on oxygen uptake at exercise onset

Chest
R CasaburiK Wasserman

Abstract

At the onset of exercise, both cardiac output and ventilation increase abruptly. We investigated the hypothesis that a rapid change in cardiac output, as effected by an immediate increase in heart rate at the start of exercise and a decrease in heart rate at the termination of exercise, affects the responses of oxygen uptake. Five patients in whom programmable pacemakers had been previously inserted for complete heart block were studied. Responses in ventilation and gas exchange were recorded breath by breath during studies in which each subject performed 16 transitions between rest and moderate exercise on a cycle ergometer. In a randomized fashion, in half of the transitions, heart rate was accelerated from a low rate to a high rate as exercise began; in the other half, heart rate was held constant at the low rate as exercise began. Oxygen uptake increased by 30 percent in the first 20 seconds of exercise, when heart rate was constrained, while it increased by 70 percent when heart rate was abruptly accelerated. Similarly, smaller changes were observed at the cessation of exercise when the heart rate was constrained, as compared to an abrupt decrease in heart rate. Despite this difference in the responses of oxygen uptake, at...Continue Reading

Citations

Jan 1, 1992·European Journal of Applied Physiology and Occupational Physiology·C J Kelsey, J Duffin
Jan 1, 1995·European Journal of Applied Physiology and Occupational Physiology·J H Mateika, J Duffin
Aug 1, 1993·Journal of Medical Systems·S SakamotoH Matsuo
Oct 27, 2004·European Journal of Applied Physiology·K KoppoJ Bouckaert
Aug 28, 2009·European Journal of Applied Physiology·Pierantonio LavenezianaDenis E O'Donnell
Jul 1, 1990·Journal of the American College of Cardiology·A C SolalR Gourgon
Oct 1, 1990·Pacing and Clinical Electrophysiology : PACE·C P LauW H Leung
Sep 1, 1994·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·S A Ward
Nov 1, 1990·The Journal of Clinical Investigation·A KoikeD Weiler-Ravell
Apr 1, 2008·Annals of the New York Academy of Sciences·Haiying ZhouMarco E Cabrera
May 22, 2009·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·Haiying ZhouMarco E Cabrera
Mar 15, 2006·Respiratory Physiology & Neurobiology·Harold J Bell

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