Effect of amblyopia treatment on choroidal thickness in hypermetropic anisometropic amblyopia using swept-source optical coherence tomography

BMC Ophthalmology
Syunsuke ArakiKiyoshi Yaoeda

Abstract

Recent studies using optical coherence tomography (OCT) have indicated that choroidal thickness (CT) in the anisometropic amblyopic eye is thicker than that of the fellow and normal control eyes. However, it has not yet been established as to how amblyopia affects the choroid thickening. The purpose of the present study was to investigate the effect of amblyopia treatment on macular CT in eyes with anisometropic amblyopia using swept-source OCT. Thirteen patients (mean age: 6.2 ± 2.4 years) with hypermetropic anisometropic amblyopia were included in this study. Visual acuity (VA), axial length (AL), and CT were measured at the enrollment visit and at the final visit, after at least 6 months of treatment. CT measurements were corrected for magnification error and were automatically analyzed using built-in software and divided into three macular regions (subfoveal choroidal thickness (SFCT), center 1 mm, and center 6 mm). A one-way analysis of covariance using AL as a covariate was performed to determine whether CT in amblyopic eyes changed after amblyopia treatment. The average observation period was 22.2 ± 11.0 months. After treatment, VA (logMAR) improvement in the amblyopic eyes was 0.41 ± 0.19 (p < 0.001). SFCT, center 1 mm ...Continue Reading

References

Nov 1, 1965·Journal of Neurophysiology·D H Hubel, T N Wiesel
Oct 9, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Robert F Hess
Aug 13, 2003·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Atsushi MikiJohn C Haselgrove
Apr 25, 2006·Lancet·Jonathan M Holmes, Michael P Clarke
Mar 18, 2009·The European Journal of Neuroscience·Robert F HessKathy T Mullen
Nov 7, 2009·Investigative Ophthalmology & Visual Science·Yasushi IkunoYoshiaki Yasuno
Jun 13, 2013·Ophthalmology·UNKNOWN Pediatric Eye Disease Investigator GroupDonny W Suh
Sep 26, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Ranjay ChakrabortyMichael J Collins
Nov 5, 2013·The British Journal of Ophthalmology·Tomo NishiNahoko Ogata
Oct 16, 2014·Investigative Ophthalmology & Visual Science·Jinling XuXinping Yu
Apr 4, 2015·European Journal of Ophthalmology·Jingjing LiMinbin Yu
Oct 9, 2015·Investigative Ophthalmology & Visual Science·Emily C Woodman-PieterseDavid Alonso-Caneiro
Oct 21, 2016·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Veysi Öner, Asker Bulut
Apr 6, 2017·International Ophthalmology·Ahmet KaderliFirdevs Örnek
Jun 21, 2017·Current Eye Research·Seray Aslan Bayhan, Hasan Ali Bayhan
Jul 14, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Maximilian GabrielSiamak Ansari-Shahrezaei
Jul 29, 2017·Journal of Ophthalmology·Yanli LiuKanxing Zhao
Oct 21, 2017·The British Journal of Ophthalmology·Sonia ToorPatricia Riddell
Dec 21, 2017·American Journal of Ophthalmology Case Reports·Ryuya HashimotoTakatoshi Maeno

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Citations

Jun 4, 2019·Seminars in Ophthalmology·Eric D GaierGena Heidary
Jul 8, 2020·Survey of Ophthalmology·Efthymia ProusaliAsimina Mataftsi

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