Effect of Amblyopia Treatment on Macular Thickness in Eyes With Myopic Anisometropic Amblyopia

Investigative Ophthalmology & Visual Science
Yi PangChristine Allison

Abstract

To determine whether abnormal macular thickness in myopic anisometropic amblyopia differed after amblyopia treatment. Furthermore, to investigate whether effect of treatment on macular thickness was associated with subject age or improvement in stereoacuity. Seventeen children (mean age: 9.0 [±3.0] years, ranging from 5.7-13.9 years) with myopic anisometropic amblyopia (visual acuity [VA] in amblyopic eyes: 20/80-20/400) were recruited and treated with 16-week refractive correction, followed by an additional 16-week refractive correction and patching. Macular thickness, best-corrected VA, and stereoacuity were measured both before and after amblyopia treatment. Factorial repeated-measures analysis of variance was performed to determine whether macular thickness in amblyopic eyes changed after amblyopia treatment. Mean baseline VA in the amblyopic eye was 1.0 ± 0.3 logMAR and improved to 0.7 ± 0.3 after amblyopia treatment (P < 0.0001). The interaction between eye and amblyopia treatment was statistically significant for average foveal thickness (P = 0.040). There was no treatment effect on fellow eyes (P = 0.245); however, the average foveal thickness in the amblyopic eye was significantly reduced after amblyopia treatment (P =...Continue Reading

Citations

Feb 17, 2017·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M FuestJ S Mehta
Jul 29, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Yi PangKelly A Frantz
Nov 23, 2019·Ophthalmic Surgery, Lasers & Imaging Retina·Savleen KaurJaspreet Sukhija
Jun 4, 2019·Seminars in Ophthalmology·Eric D GaierGena Heidary

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